業績一覧Publication List

英文論文

  • 2017年

    • Ayaka Mizumoto, Shinya Ohashi, Kenshiro Hirohashi, Yusuke Amanuma, Tomonari Matsuda, Manabu Muto

      Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.

      Int J Mol Sci (in press)

       

    • Yosuke Fujii, Yoshitaka Nishikawa, Motoo Nomura, Shin’ich Miyamto, Yu Uneno, Takahiro Horimatsu, and Manabu Muto.

      Readministration of Nivolumab after Persistent Immune-Related Colitis in a Patient with Recurrent Melanoma

      Internal Medicine (in press)

       

       

    • Yu Uneno, Kei Taneishi, Masashi Kanai, Kazuya Okamoto, Yosuke Yamamoto, Akira Yoshioka, Shuji Hiramoto, Akira Nozaki, Yoshitaka Nishikawa, Daisuke Yamaguchi, Teruko Tomono, Masahiko Nakatsui Mika Baba, Tatsuya Morita, Shigemi Matsumoto, Tomohiro Kuroda, Yasushi Okuno, Manabu Muto.  

      Development and Validation of a Set of Six Adaptable Prognosis Prediction (SAP) Models Based on Time-Series Real-World Big Data Analysis for Patients with Cancer Receiving Chemotherapy: A Multicenter Case Crossover Study.

       PLOS ONE 2017 (in press)

       

    • Masahiro Yoshioka, Shinya Ohashi, Tomomi Ida, Yukie Nakai, Osamu Kikuchi, Yusuke Amanuma, Junichi Matsubara, Atsushi Yamada, Shin’ichi Miyamoto, Mitsuteru Natsuizaka, Hiroshi Nakagawa,Tsutomu Chiba, Hiroshi Seno, Manabu Muto.

      Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

      J Exp Clin Cancer Res (in press)

    • Peng Xue, Junjie Hang, Weiyi Huang, Shaobo Li, Ning Li, Yuzo Kodama, Shigemi Matsumoto, Kyoichi Takaori, Lifei Zhu, Masashi Kanai

      Validation of Lymphocyte to Monocyte Ratio As a Prognostic Factor in Advanced Pancreatic Cancer: An East Asian Cohort Study of Two Countries

      Pancreas(in press)

       

       

    • Takahiro Horimatsu, Norisuke Nakayama, Toshikazu Moriwaki, Yoshinori Hirashima, Mikio Fujita, Masako Asayama, Ichiro Moriyama, Koji Nakashima, Eishi Baba, Hiroshi Kitamura, Takao Tamura, Ayumu Hosokawa, Kenichi Yoshimura, Manabu Muto.

       A phase II study of 5-FU/l-LV/oxaliplatin (mFOLFOX6) in Japanese patients with metastatic or unresectable small bowel adenocarcinoma

       Int J Clin Oncol(in press)

       

    • Masashi Tamaoki, Yasumasa Ezoe1, Ikuo Aoyama, Takahiro Horimatsu, Shuko Morita, Shin’ichi Miyamoto, Shigemi Matsumoto, Tsutomu Chiba, and Manabu Muto.

      S-1 Salvage Chemotherapy for Esophageal Squamous Cell Carcinoma Refractory to the Standard Chemotherapy.

      Journal of Cancer Science & Therapy.2017;9(3):353-357.

    • Kitayama H, Kondo T, Sugiyama J, Kurimoto K, Nishino Y, Hirayama M, Tsuji Y.

      Venous thromboembolism in hospitalized patients receiving chemotherapy for malignancies at Japanese community hospital: prospective observational study.

      BMC Cancer.2017 17:351.

    • Kitayama H, Kondo T, Sugiyama J, Kurimoto K, Nishino Y, Kawada M, Hirayama M, Tsuji Y.

      High-sensitive troponin T assay can predict anthracycline- and trastuzumab-induced cardiotoxicity in breast cancer patients.

      Breast Cancer. 2017. [Epub ahead of print].

    • Yoshitaka Nishikawa, Masashi Kanai, Maiko Narahara,Akiko Tamon, JB Brown , Kei Taneishi, Masahiko Nakatsui, Kazuya Okamoto, Yu Uneno, Daisuke Yamaguchi, Teruko Tomono,Yukiko Mori, Shigemi Matsumoto, Yasushi Okuno, and Manabu Muto.

      Association between UGT1A1*28*28 genotype and lung cancer in the Japanese population

      Int J Clin Oncol.(2017) 22:269–273

    • Ito T, Honma Y, Hijioka S, Kudo A, Fukutomi A, Nozaki A, Kimura Y, Motoi F, Isayama H, Komoto I, Hisamatsu S, Nakajima A, Shimatsu A.

      Phase II study of lanreotide autogel in Japanese patients with unresectable or metastatic well-differentiated neuroendocrine tumors.

      Invest New Drugs.August 2017, Volume 35, Issue 4,  pp 499–508

    • Aizawa R, Matsumoto S, Uneno Y, Nishikawa Y, Ozaki Y, Mori Y, Kanai M, Ishida Y, Sakanaka K, Hiraoka M, Muto M.

      Severe esophagitis associated with cytomegalovirus during concurrent chemoradiotherapy for esophageal cancer.

      Japanese Journal of Clinical Oncology [07 Jun 2017:1-4]

       

       

       

    • Nishimura T, Tamaoki M, Komatsuzaki R, Oue N, Taniguchi H, Komatsu M, Aoyagi K, Minashi K, Chiwaki F, Shinohara H, Tachimori Y, Yasui W, Muto M, Yoshida T, Sakai Y, Sasaki H.

      SIX1 maintains tumor basal cells via transforming growth factor-β pathway and associates with poor prognosis in esophageal cancer.

      Cancer Sci. 2017 Feb;108(2):216-225.

       

    • Ikuo Aoyama, Shinya Ohashi, Yusuke Amanuma, Kenshiro Hirohashi, Ayaka Mizumoto, Makiko Funakoshi, Mihoko Tsurumaki, Yukie Nakai, Katsuyuki Tanaka, Mariko Hanada, Aki Uesaka, Tsutomu Chiba, Manabu Muto.

      Establishment of a quick and highly accurate breath test for ALDH2 genotyping

      Clin Transl Gastroenterol. 2017 Jun 8;8(6):e96.

       

    • Tadayuki Kou, Masashi Kanai, Yoshihiro Yamamoto, Mayumi Kamada, Masahiko Nakatsui, Tomohiro Sakuma, Hiroaki Mochizuki, Akinori Hiroshima, Aiko Sugiyama, Eijiro Nakamura, Hidehiko Miyake, Sachiko Minamiguchi, Kyoichi Takaori, Shigemi Matsumoto, Hironori Haga, Hiroshi Seno, Shinji Kosugi, Yasushi Okuno, Manabu Muto.

      Clinical Sequencing Using a Next-Generation Sequencing-Based Multiplex Gene Assay in Patients with Advanced Solid Tumors

      Cancer Sci. 2017 Jul;108(7):1440-1446.

       

       

    • Nagayama S, Hasegawa S, Hida K, Kawada K, Hatano E, Nakamura K, Seo S, Taura K, Yasuchika K, Matsuo T, Zaima M, Kanazawa A, Terajima H, Tada M, Adachi Y, Nishitai R, Manaka D, Yoshimura T, Doi K, Horimatsu T, Mitsuyoshi A, Yoshimura K, Niimi M, Matsumoto S, Sakai Y, Uemoto S.

      Multi-institutional phase II study on the feasibility of liver resection following preoperative mFOLFOX6 therapy for resectable liver metastases from colorectal cancers.

      Int J Clin Oncol (2017) 22:316–323

       

       

    • Yano T, Yoda Y, Nomura S, Toyosaki K, Hasegawa H, Ono H, Tanaka M, Morimoto H, Horimatsu T, Nonaka S, Kaneko K, Sato A.

      Prospective trial of biodegradable stents for refractory benign esophageal strictures after curative treatment of esophageal cancer.

      Gastrointest Endosc. 2017 Jan 27(in press)

       

    • Hirakawa H, Nakashima C, Nakamura T, Masuda M, Funakoshi T, Nakagawa S, Horimatsu T, Matsubara K, Muto M, Kimura S, Sueoka-Aragane N.

      Chemotherapy for primary mediastinal yolk sac tumor in a patient undergoing chronic hemodialysis: a case report.

      J Med Case Rep. 2017 Feb 16;11(1):43

       

    • Nomura M, Kato K, Ando N, Ohtsu A, Muro K, Igaki H, Abe T, Takeuchi H, Daiko H, Gotoh M, Kataoka K, Wakabayashi M, Kitagawa Y.

      Comparison between neoadjuvant chemotherapy followed by surgery and definitive chemoradiotherapy for overall survival in patients with clinical Stage II/III esophageal squamous cell carcinoma (JCOG1406-A).

      Jpn J Clin Oncol. 2017  Mar 17:1-7.

    • Akira Yokoyama, Chikatoshi Katada, Tetsuji Yokoyama, Tomonori Yano, Kazuhiro Kaneko, Ichiro Oda, Yuichi Shimizu, Hisashi Doyama, Tomoyuki Koike, Kohei Takizawa, Motohiro Hirao, Hiroyuki Okada, Takako Yoshii, Kazuo Konishi, Takenori Yamanouchi, Takashi Tsuda, Tai Omori, Nozomu Kobayashi, Haruhisa Suzuki, Satoshi Tanabe, Keisuke Hori, Norisuke Nakayama, Hirofumi Kawakubo, Hideki Ishikawa, Manabu Muto.

      Alcohol abstinence and risk assessment for second esophageal cancer in Japanese men after mucosectomy for early esophageal cancer.

      PLoS One. 2017 Apr 6;12(4):e0175182

       

       

    • Tomonori Yano, Hiroi Kasai, Takahiro Horimatsu, Kenichi Yoshimura, Satoshi,Teramukai, Satoshi Morita, Harue Tada, Yoshinobu Yamamoto, Hiromi Kataoka,Naomi Kakushima, Ryu Ishihara, Hajime Isomoto, Manabu Muto

      A multicenter phase II study of salvage photodynamic therapy using talaporfin sodium (ME2906) and a diode laser (PNL6405EPG) for local failure after chemoradiotherapy or radiotherapy for esophageal cancer

      Oncotarget 2017 Mar 28;8(13):22135-22144.

       

    • Seiji Ishikawa, Ichiro Tateya, Takahiro Hayasaka, Satoru Shinriki, Noritaka Masaki, Shigeru Hirano, Morimasa Kitamura, Manabu Muto, Shuko Morita, Mitsutoshi Setou, Juichi Ito.

      The distribution of Phosphatidylcholine species in superficial-type pharyngeal carcinoma

      Biomed Res Int. 2017 Mar 8(in press)

       

    • Yoshitaka Nishikawa, Taro Funakoshi, Takahiro Horimatsu, Shinichi Miyamoto, Takeshi Matsubara, Motoko Yanagita, Shunsaku Nakagawa, Atsushi Yonezawa, Kazuo Matsubara, Manabu Muto.

      Accumulation of alpha-fluoro-beta-alanine and fluoro mono acetate in a patient with 5-fluorouracil-associated hyperammonemia

      Cancer Chemother Pharmacol. 2017 Mar;79(3):629-633

       

       

       

       

       

       

    • Deguchi Y, Okabe H, Oshima Y, Hisamori S, Minamiguchi S, Muto M, Sakai Y.

      PTEN loss is associated with a poor response to trastuzumab in HER2-overexpressing gastroesophageal adenocarcinoma

      Gastric Cancer. 2017 May;20(3):416-427.

       

       

    • Kenshi Yao, Noriya Uedo, Manabu Muto, Hideki Ishikawa

      Development of an e-learning system for teaching endoscopists how to diagnose early gastric cancer: basic principles for improving early detection

      Gastric Cancer 2017 Mar;20(Suppl 1):28-38.

    • Yamamura K, Otsuka A, Kaku Y, Seidel JA, Nomura M, Nagai H, Matsumoto S, Kabashima K.

      Dermoscopic changes in malignant melanoma after successful treatment with nivolumab: A case report

      J Dermatol.  2017 May;44(5):547-548

       

    • Manabu Muto

      Biobank and informatics for cancer projects and clinical sequencing at Kyoto University Cancer Center

      Clin Eval 45(1) 2017 189-193

       

  • 2016年

    • Sano Y, Tanaka S, Kudo S, Saito S, Matsuda T, Wada Y, Fujii T, Ikematsu H, Uraoka T, Kobayashi N, Nakamura H, Hotta K,Horimatsu T, Sakamoto N, Fu KI, Tsuruta O, Kawano H, Kashida H, Takeuchi Y, Machida H, Kusaka T, Yoshida N, Hirata I,Terai T, Yamano HO, Kaneko K,Nakajima T, Sakamoto T, Yamaguchi Y, Tamai N, Nakano N, Hayashi N, Oka S, Iwatate M, Ishikawa H, Murakami Y, Yoshida S, Saito Y

      Narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team.

      Dig Endosc. 2016 Jul;28(5):526-33.

       

       

       

       

    • Maeda A, Ura T, Asano C, Haegawa I, Nomura M, Komori A, Narita Y, Taniguchi H, Kadowaki S, Muro K, Horio Y, Yoshida T, Oze I, Kajita M, Mizutani A.

      A phase II trial of prophylactic olanzapine combined with palonosetron and dexamethasone for preventing nausea and vomiting induced by cisplatin

      Asia Pac J Clin Oncol 2016 Sep;12(3):254-8.

       

    • Koji Tanaka, Kelly A Whelan,Prasanna M Chandramouleeswaran, Shingo Kagawa, Sabrina L Rustgi, Chiaki Noguchi, Manti Guha,Satish Srinivasan, Yusuke Amanuma, Shinya Ohashi, Manabu Muto,Andres J Klein-Szanto, Eishi Noguchi,Narayan G Avadhani.

      ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds

      Am J Cancer Res. 6(4):781-796, 2016.

       

    • Yoshitaka Nishikawa, Shin’ichi Miyamoto, Takahiro Horimatsu,  Hiroshi Okabe, Manabu Muto.

      Esophageal rupture associated with colonoscopy preparation.

      J Am Geriatr Soc.  Mar;64(3):682-3 2016

    • Nishiakawa Y, Sakurai T, Miyamoto S

      Multiple White Plaques in the Body of the Stomach in a Patient Undergoing Hemodialysis

      Gastroenterology 151(1):e18-e19, 2016.

       

    • Kohei Takizawa, Hiroyuki Ono, Yorimasa Yamamoto, Hitoshi Katai, Shinichiro Hori, Tomonori Yano, Eiji Umegaki, Shunya Sasaki, Toshiro Iizuka, Kei Kawagoe, Tadakazu Shimoda, Manabu Muto, Mitsuru Sasako.

      Incidence of lymph node metastasis in intramucosal gastric cancer measuring ≤30 mm, with ulceration; mixed, predominantly differentiated-type histology; and no lymphovascular invasion: a multicenter retrospective study

      Gastric Cancer 19(4):1144-1148, 2016.

       

    • Kato H, Kitagawa Y, Kuwano H, Toh Y, Kusano M, Oyama T, Muto M, Takeuchi H, Doki Y, Naomoto Y, Nemoto K, Matsubara H, Miyazaki T, Yanagisawa A, Uno T, Kato K, Yoshida M, Kawakubo H, Booka E, Nakajima M, Kaneko K, Shiotani A

      Neo-adjuvant therapy or definitive chemoradiotherapy can improve laryngeal preservation rates in patients with cervical esophageal cancer. A Japanese nationwide survey

      Esophagus 13(3):276-282, 2016

    • Tateya I, Muto M, Morita S, Miyamoto S, Hayashi T, Funakoshi M,  Aoyama, I Higuchi H, Hirano S, Kitamura M, Ishikawa S, Kishimoto Y, Morita M, Ito J

      Endoscopic laryngo-pharyngeal surgery for superficial laryngopharyngeal cancer.

      Surg Endosc. 30(1):323-329, 2016.

    • Yuichiro Kitai, Takeshi Matsubara, Taro Funakoshi, Takahiro Horimatsu, Manabu Muto, Motoko Yanagita

      Cancer screening and treatment in patients with end-stage renal disease: remaining issues in the field of onco-nephrology ; Invited review article by Japanese Society for Dialysis Therapy

      Renal Replacement Therapy 2:33, 2016

    • Kakushima N, Hori K, Ono H, Horimatsu T, Uedo N, Ohata K, Doyama H, Kaneko K, Oda I, Hikichi T, Kawahara Y, Niimi K, Takaki Y, Mizuno M, Yazumi S, Hosokawa A, Imagawa A, Niimi M, Yoshimura K, Muto M

      Proton pump inhibitor after endoscopic resection for esophageal squamous cell cancer: multicenter prospective randomized controlled trial

      J Gastroenterol. 51(2):104-111, 2016.

       

       

    • Yukiko Mori, Satoshi Nagayama, Jun-ichiro Kawamura, Suguru Hasegawa, Eiji Tanaka, Hiroshi Okabe, Megumi Takeuchi, Makoto Sonobe, Shigemi Matsumoto, Masashi Kanai, Manabu Muto, Tsutomu Chiba, Yoshiharu Sakai.

      A retrospective analysis on the utility and complications of upper arm ports in 433 cases at a single institute.

      Int J Clin Oncol 21(3):474-482, 2016.

       

    • Kou T, Kanai M, Yamamoto M, Xue P, Mori Y, Kudo Y, Kurita A, Uza N, Kodama Y, Asada M, Kawaguchi M, Masui T, Mizumoto M, Yazumi S, Matsumoto S, Takaori K, Morita S, Muto M, Uemoto S, Chiba T.

      Prognostic model for survival based on readily available pretreatment factors in patients with advanced pancreatic cancer receiving palliative chemotherapy

      Int J Clin Oncol 21(1):118-125, 2016.

       

    • Koichi Inoue, Motoo Nomura

      Assay for Fentanyl

      In Victor R. Preedy (ed): The Neuropathology of Drug Addictions and Substance Misuse Volume 3, 1st Edition. Netherlands, Amsterdam, Elsevier B.V. 2016;619-630.

    • Toh Y, Kitagawa Y, Kuwano H, Kusano M, Oyama T, Muto M, Kato H, Takeuchi H, Doki Y, Nomoto Y, Nemoto K, Matsubar H, Miyazaki T, Yanagisawa A, Uno T, Kato K, Yoshidam M, Kawakubo H, Booka E.

      A Nation-wide Survey of Follow-up Strategies for Esophageal Cancer Patients after a Curative Esophagectomy or a Complete Response by Definitive Chemoradiotherapy in Japan

      Esophagus 13(2):173-181, 2016

    • Katada C, Yokoyama T, Yano T, Kaneko K, Oda I, Shimizu Y, Doyama H, Koike T, Takizawa K, Hirao M, Okada H, Yoshii T, Konishi K, Yamanouchi T, Tsuda T, Omori T, Kobayashi N, Shimoda T, Ochiai A, Amanuma Y, Ohashi S, Matsuda T, Ishikawa H, Yokoyama A, Muto M.

      Alcohol consumption and multiple dysplastic lesions increase risk of squamous cell carcinoma in the esophagus, head, and neck

      Gastroenterology 151(5):860-869, 2016.

       

       

    • Manabu Muto, Kenshi Yao, Mitsuru Kaise, Mototsugu Kato, Noriya Uedo, Kazuyoshi Yagi, Hisao Tajiri

      Magnigying endoscopy simple diagnostic algorithm for early gastric cancer

      Dig Endosc 28(4):379-393, 2016.

       

    • Ichiro Tateya, Shuko Morita, Seiji Ishikawa, Manabu Muto, Shigeru Hirano, Yo Kishimoto, Nao Hiwatashi, Juichi Ito.

      Voice outcome in patients treated with endoscopic laryngopharyngeal surgery for superficial hypopharyngeal cancer

      Clin Exp Otorhinolaryngol. 9(1):70-74, 2016.

       

    • Ichiro Tateya, Akihiro Shiotanik Yasuto Satou, Masayuki Tomifuji, Shuko Morita, Manabu Muto, Juichi Ito

      Transoral surgery for laryngo-pharyngeal cancer-The paradigm shift of the head and cancer treatment

      Auris Nasus Larynx 43(1):21-32, 2016.

       

    • Nomura M, Iwasa S, Tsushima T, Kato K, Yasui H, Boku N, Muto M, Muro K.

      Active salvage chemotherapy versus best supportive care for patients with recurrent or metastatic squamous cell carcinoma of the esophagus refractory or intolerable to fluorouracil, platinum, and taxane.

      Cancer Chemother Pharmacol. 2016 Dec;78(6):1209-1216.

       

       

       

       

    • Yu Uneno, Akira Yokoyama, Yoshitaka Nishikawa, Taro Funakoshi, Yoshinao Ozaki, Ikuo Aoyama, Kiichiro Baba, Daisuke Yamaguchi, Shuko Morita, Yukiko Mori, Masashi Kanai, Hisanori Kinoshita, Takeshi Inoue, Nobukatsu Sawamoto, Riki Matsumoto, Shigemi Matsumoto, Manabu Muto.

      Paraneoplastic limbic encephalitis in human epidermal growth factor receptor-2-positive gastric cancer patient treated with trastuzumab-combined chemotherapy: case report and literature review.

      Internal Medicine 55(18):2605-2609, 2016.

    • Yoshitaka Nishikawa, Hirokazu Higuchi, Osamu Kikuchi, Yasumasa Ezoe, Ikuo Aoyama, Atsushi Yamada, Masataka Kanki, Shuhei Nomura, Motoo Nomura, Takahiro Horimatsu and Manabu Muto.

      Factors affecting dilation force in balloon dilation of severe esophageal strictures: an experiment using an artificial stricture model

      Surgical Endoscopy 30(10):4315-4320, 2016.

    • Okuno M, Hatano E, Kasai Y, Nishio T, Seo S, Taura K, Yasuchika K, Nitta T, Mori A, Okajima H, Kaido T, Hasegawa S, Matsumoto S, Sakai Y, Uemoto S.

      Feasibility of the liver-first approach for patients with initially unresectable and not optimally resectable synchronous colorectal liver metastases.

      Surg Today (2016) 46:721–728

       

    • Hironaka S, Sugimoto N, Yamaguchi K, Moriwaki T, Komatsu Y, Nishina T, Tsuji A, Nakajima TE, Gotoh M, Machida N, Bando H, Esaki T, Emi Y, Sekikawa T, Matsumoto S, Takeuchi M, Boku N, Baba H, Hyodo I.

      S-1 plus leucovorin versus S-1 plus leucovorin and oxaliplatin versus S-1 plus cisplatin in patients with advanced gastric cancer: a randomised, multicentre, open-label, phase 2 trial.

      The Lancet. Oncology,17,1,99-108

    • Kondo T, Kitayama H, Sugiyama J, Hirayama M, Suzuki Y, Oyamada Y, Tsuji Y.

      Conversion therapy of gastric cancer with massive malignant ascites and ovarian metastases by systemic and intraperitoneal chemotherapy.

      Mol Clin Oncol.5:740-744, 2016.

    • Kitayama H, Kondo T, Sugiyama J, Hirayama M, Oyamada Y, Tsuji Y.

      Conversion therapy for pancreatic cancer having peritoneal metastases by intravenous and intraperitoneal paclitaxel with S-1.

      Mol Clin Oncol.5:779-782, 2016.

    • Kitayama H, Kondo T, Sugiyama J, Hirayama M, Oyamada Y, Tsuji Y.

      Paraneoplastic erythrocytosis of colon cancer, with serum erythropoietin within the normal reference

      Am J Case Rep.17:417-420, 2016.

       

    • Kitayama H, Yokota T, Kondo T, Sugiyama J, Hirayama M, Oyamada Y, Tsuji Y.

      Unusual Development of Pulmonary Tumor Embolism from Controlled Liver Metastases of Transitional Cell Carcinoma

      An Autopsy Case. Intern Med. 55:2453-1456, 2016.

    • Ishizu S, Setoyama T, Ueo T, Ueda Y, Kodama Y, Ida H, Kawaguchi Y, Yoshizawa A, Chiba T, Miyamoto S.

      Concomitant case of intraductal papillary mucinous neoplasm of the pancreas and functioning pancreatic neuroendocrine tumor (Vasoactive intestinal polypeptide-producing tumor) first report.

      Pancreas 2016; 45: e24-e25.

    • Kanai M, Kawaguchi T, Kotaka M, Shinozaki K, Touyama T, Manaka D, Ishigure K, Hasegawa J, Munemoto Y, Matsui T, Takagane A, Ishikawa H, Matsumoto S, Sakamoto J, Saji S, Yoshino T, Ohtsu A, Watanabe T, Matsuda F.

      Large-scale prospective pharmacogenomics study of oxaliplatin-induced neuropathy in colon cancer patients enrolled in the JFMC41-1001-C2 (JOIN Trial).

      Ann Oncol. 2016 Jun;27(6):1143-8.

    • Hamada K, Takeuchi Y, Ishikawa H, Tonai Y, Matsuura N, Ezoe Y, Ishihara R, Tomita Y, Iishi H

      Feasibility of Cold Snare Polypectomy for Multiple Duodenal Adenomas in Patients with Familial Adenomatous Polyposis: A Pilot Study

      Dig Dis Sci. 2016 Sep;61(9):2755-9.

    • Katsuyuki Sakanaka, Manabu Muto, et al.
      Identification of a Predictive Factor for Distant Metastasis in Esophageal Squamous Cell Carcinoma after Definitive Chemoradiotherapy.
      Int J Clin Oncol. 2016 Oct;21(5):899-908.

    • Motoo Nomura, Isao Oze, Takeshi Kodaira, Tetsuya Abe, Azusa Komori, Yukiya Narita, Toshiki Masuishi, Hiroya Taniguchi, Shigenori Kadowaki, Takashi Ura, Masashi Andoh, Hiroyuki Tachibana, Norihisa Uemura, Masahiro Tajika, Yasumasa Niwa, Manabu Muto, Kei Muro.

      Comparison between surgery and definitive chemoradiotherapy for patients with resectable esophageal squamous cell carcinoma: a propensity score analysis

      Int J Clin Oncol. 2016 Oct;21(5):890-898. 

    • Osamu Kikuchi, Shinya Ohashi, Tomohisa Horibe, Masayuki Kohno, Yukie Nakai, Shin’ichi Miyamoto, Tsutomu Chiba, Manabu Muto, and Koji Kawakami.

      Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma

      Sci Rep. 2016 Mar 9;6:22452 

    • Tadayuki Kou, Masashi Kanai, Shigemi Matsumoto, Yasushi Okuno, Manabu Muto.

      The possibility of clinical sequencing in the management of cancer.

      Jpn J Clin Oncol 46(5):399-406,2016.

  • 2015年

    • Tanaka Y, Aoyagi K, Minashi K, Komatsuzaki R, Komatsu M, Chiwaki F, Tamaoki M, Nishimura T, Takahashi N, Oda I, Tachimori Y, Arao T, Nishio K, Kitano S, Narumi K, Aoki K, Fujii S, Ochiai A, Yoshida T, Muto M, Yamada Y, Sasaki H.

      Discovery of a Good Responder Subtype of Esophageal Squamous Cell Carcinoma with Cytotoxic T-Lymphocyte Signatures Activated by Chemoradiotherapy.

      PLoS One. 2015 Dec 1;10(12):e0143804.

    • Shinya Ohashi, Shin’ichi Miyamoto, Osamu Kikuchi, Tomoyuki Goto,  Yusuke Amanuma, and  Manabu Muto.

      Recent Advances from Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma.

      Gastroenterology 2015 Dec;149(7):1700-15. 

    • Horimatsu T, Miyamoto S, Mashimo Y, Okabe H, Mikami Y, Chiba T, Muto M.

      Pseudo-Meigs’ Syndrome Caused by a Krukenberg Tumour of Gastric Cancer.

      Intern Med. 2015;54(20):2595-7.

    • Setoyama T, Miyamoto S, Nikaido M, Muto M, Chiba T.

      Instability of IGF-IGFBP complex as a cause of the different performance of serum and EDTA-plasma after storage: EDTA-plasma is preferable for evaluating bioactive IGF especially in the mouse.

      Growth Horm IGF Res. 2015 Oct;25(5):227-31. 

    • Yusuke Amanuma, Shinya Ohashi, Yoshiro Itatani, Mihoko Tsurumaki, Shun Matsuda, Osamu Kikuchi, Yukie Nakai, Shin’ichi Miyamoto, Tsunehiro Oyama, Toshihiro Kawamoto, Kelly Whelan, Hiroshi Nakagawa, Tsutomu Chiba, Tomonari Matsuda, and Manabu Muto.

      Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.

      Scientific Reports 2015 Sep 16;5:14142.

    • Yamada A, Horimatsu T, Okugawa Y, Nishida N, Honjo H, Ida H, Kou T, Kusaka T, Sasaki Y, Makato Y, Higurashi T, Yukawa N, Amanuma Y, Kikuchi O, Muto M, Ueno Y, Nakajima A, Chiba T, Boland CR, Goel A.

      Serum miR-21, miR-29a and miR-125b are promising biomarkers for the early detection of colorectal neoplasia.

      Clin Cancer Res2015 Sep 15;21(18):4234-42. 

    • Sato F, Kubota Y, Natsuizaka M, Maehara O, Hatanaka Y, Marukawa K, Terashita K, Suda G, Ohnishi S, Shimizu Y, Komatsu Y, Ohashi S, Kagawa S, Kimugasa H, Whelan KA, Nakagawa H, Sakamoto N.

      EGFR inhibitors prevent induction of cancer stem-like cells in esophageal squamous cell carcinoma by suppressing epithelial-mesenchymal transition.

      Cancer Biol Ther. 2015, 16(6) : 933-40

    • Fujiwara Y, Kobayashi S, Nagano H, Kanai M, Hatano E, Toyoda M, Ajiki T, Takashima Y, Yoshimura K, Hamada A, Minami H, Ioka T.

      Pharmacokinetic Study of Adjuvant Gemcitabine Therapy for Biliary Tract Cancer following Major Hepatectomy (KHBO1101).

      PLoS One. 2015 Dec 3;10(12):e0143072.

    • Kishi T, Nakamura A, Itasaka S, Shibuya K, Matsumoto S, Kanai M, Kodama Y, Takaori K, Mizowaki T, Hiraoka M.

      Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.

      Pancreatology. 2015 Nov-Dec;15(6):694-700

    • Hamanishi J, Mandai M, Ikeda T, Minami M, Kawaguchi A, Murayama T, Kanai M, Mori Y, Matsumoto S, Chikuma S, Matsumura N, Abiko K, Baba T, Yamaguchi K, Ueda A, Hosoe Y, Morita S, Yokode M, Shimizu A, Honjo T, Konishi I.

      Safety and anti-tumor activity of anti-PD-1 antibody (nivolumab: BMS-936558, ONO-4538) in patients with platinum-resistant ovarian cancer.

      J Clin Oncol. 2015 Dec 1;33(34):4015-22.

    • Hatano E, Kanai M, Nagano H, Ioka T.

      Clinical study of new chemotherapy regimen for biliary tract cancer.

      Nihon Rinsho. 2015 Mar;73 Suppl 3:805-8.

       

       

    • Kitayama H, Tsuji Y, Sugiyama J, Doi A, Kondo T, Hirayama M.

      Efficacy of palonosetron and 1-day dexamethasone in moderately emetogenic chemotherapy compared with fosaprepitant, granisetron, and dexamethasone: a prospective randomized crossover study.

      Int J Clin Oncol. 20:1051- 1056, 2015.

    • Kanai M, Hatano E, Kobayashi S, Fujiwara Y, Marubashi S, Miyamoto A, Shiomi H, Kubo S, Ikuta S, Yanagimoto H, Terajima H, Ikoma H, Sakai D, Kodama Y, Seo S, Morita S, Ajiki T, Nagano H, Ioka T.

      A multi-institution phase II study of gemcitabine/cisplatin/S-1 (GCS) combination chemotherapy for patients with advanced biliary tract cancer (KHBO 1002).

      Cancer Chemother Pharmacol. 2015 Feb; 75(2):293-300.

       

    • Nomura M, Oze I, Abe T, Komori A, Narita Y, Masuishi T, Taniguchi H, Kadowaki S, Ura T, Andoh M, Kawai R, Uemura N, Ishihara M, Tanaka T, Tajika M, Niwa Y, Muro K, Muto M.

      Impact of docetaxel in addition to cisplatin and fluorouracil as neoadjuvant treatment for resectable stage III or T3 esophageal cancer: a propensity score-matched analysis.

      Cancer Chemother Pharmacol 2015 Aug;76(2):357-63.

    • Osamu kikuchi, Shinya Ohashi, Yukie Nakai, Shunsaku Nakagawa, Kazuaki Matsuoka, Takashi Kobunai,  Teiji Takechi, Yusuke Amanuma, Masahiro Yoshioka, Tomomi Ida, Yoshihiro Yamamoto, Yasushi Okuno,Shin’ichi Miyamoto, Hiroshi Nakagawa, Kazuo Matsubara, Tsutomu Chiba, and Manabu Muto.

      Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.

      American Journal of Cancer Research 2015 Jul 15;5(8):2431-40. eCollection 2015.

    • Ichiro Tateya, Shuko Morita, Manabu Muto, Shinichi Miyamoto, Tomomasa Hayashi, Makiko Funakoshi, Ikuo Aoyama, Shigeru Hirano, Morimasa Kitamura, Seiji Ishikawa, Yo Kishimoto, Mami Morita, Patnarin Mahattanasakul, Satoshi Morita, Juishi Ito

      Magnifying endoscope with NBI topredict the depth of invasion in laryngo-pharyngeal cancer

      Laryngoscope 125(5):1124-1129, 2015.

    • Kozo Katanaoka, Ikuo Aoyama, Junnki Mizusawa, Junko Eba, Keiko Minashi, Tomonori Yano Masaki Tanaka, Noboru Hanaoka, Hiroshi Katayama, Kohei Takizawa, Haruhiko Fukuda, Manabu Muto on behalf of the Gastrointestinal Endoscopy Study Group(GIESG)of the Japan Clinical Oncology Group.

      A randomized controlled Phase II/III study comparing endoscopic balloon dilation combined with steroid injection versus radial incision and cutting combined with steroid injection for refractory anastomotic stricture after esophagectomy:

      Jpn J Clin Oncol. 2015 Apr;45(4):385-9.

    • Tomonori Mizutani, Masaki Tanaka, Junko Eba, Junki Mizusawa, Haruhiko Fukuda, Nonobu Hanaoka, Manabu Takeuchi, Ikuo Aoyama, Takashi Kojima, Kohei Takizawa, Hiroyuki Ono, Manabu Muto.

      A Phase III study of oral steroid administration versus local steroid injection therapy for the prevention of esophageal stricture after endoscopic submucosal dissection (JCOG1217, Steroid EESD P3)

      Jpn J Clin Oncol 45(11):1087-1090, 2015.

    • Hatano E, Okuno M, Nakamura K, Ishii T, Seo S, Taura K, Yasuchika K, Yazawa T, Zaima M, Kanazawa A, Terajima H, Kaihara S, Adachi Y, Inoue N, Furumoto K, Manaka D, Tokka A, Furuyama H, Doi K, Hirose T, Horimatsu T, Hasegawa S, Matsumoto S, Sakai Y, Uemoto S.

      Conversion to complete resection with mFOLFOX6 with bevacizumab or cetuximab based on K-ras status for unresectable colorectal liver metastasis (BECK study)

      J Hepatobiliary Pancreat Sci 22(8):634-645, 2015

    • Horimatsu T, Sano Y, Tanaka S, Kawamura T, Saito S, Iwatate M, Oka S, Uno K, Yoshimura K, Ishikawa H, Muto M, Tajiri H.

      Next-generation narrow band imaging system for colonic polyp detection: a prospective multicenter randomized trial

      Int J Colorectal Dis. 30(7):947-54

       

    • Ishikawa S, Tateya I, Hayasaka T, Masak Ni, Hirano S, Kitamura M, Muto M, Morita S, Setou M, Ito J.

      Phosphatidylcholine with arachidonic acid was increased in the submucosal microinvasive region of hypopharyngeal carcinoma

      Head Neck.2015

       

    • Nikaido M, Miyamoto S, Iinuma S.

      Prevention of gastric volvulus-induced recurrent acute pancreatitis by percutaneous endoscopic gastropexy

      Gastroenterol Hepatol 13(2):e11-e12:2015.

       

    • Hiroyuki Kuwano, Yasumasa Nishimura, Tsuneo Oyama, Hiroyuki Kato, Yuko Kitagawa, Motoyasu Kusano, Hideo Shimada, Hiroya Takiuchi, Yasushi Toh, Yuichiro Doki, Yoshio Naomoto, Hisahiro Matsubara, Tatsuya Miyazaki, Manabu Muto, Akio Yanagisawa

      Guidelines for diagnosis and treatment of caarcinoma of the esophagus April 2012 edited by the Japan Esophageal Society

      Esophagus 12:1-30,2015

       

    • Kanesaka T, Uedo N, Yao K, Ezoe Y, Doyama H, Oda I, Kaneko K, Kawahara Y, Yokoi C, Sugiura Y, Ishikawa H, Kato M, Takeuchi Y, Muto M, Saito Y.

      A significant feature of microvessels in magnifying narrow-band imaging for diagnosis of early gastric cancer

      Endosoc Int Open 2015 3(6):E590-E596, 2015.

       

    • Satake H, Yano T, Muto M, Minashi K, Yoda Y, Kojima T, Oono Y, Ikematsu H, Aoyama I, Morita S, Miyamoto S, Fujii S, Yoshizawa A, Ochiai A, Hayashi R, Kaneko K.

      Clinical outcome after endoscopic resection for superficial pharyngeal squamous cell carcinoma invading the subepithelial layer

      Endoscopy 47(1):11-18,2015

       

    • Hayashi K, Fujiwara Y, Nomura M, Kamata M, Kojima H, Kohzai M, Sumita K, Tanigawa N.

      Predictive factors for pericardial effusion identified by heart dose-volume histogram analysis in oesophageal cancer patients treated with chemoradiotherapy.

      Br J Radiol 2015 Feb;88(1046):20140168.

       

       

    • Chihiro Kondoh, Kohei Shitara, Motoo Nomura, Daisuke Takahari, Takashi Ura, Hiroyuki Tachibana, Natsuo Tomita, Takeshi Kodaira, Kei Muro

      Efficacy of palliative radiotherapy for gastric bleeding in patients with unresectable advanced gastric cancer: a retrospective cohort study

      BMC Palliat Care.  4(14)37, 2015

    • Kyoko Murata, Shiro Hinotsu, Shota Hamada, Yasumasa Ezoe, Manabu Muto , Koji Kawakami

      The changing patterns of dispensing branded and generic drugs for the treatment of gastroesophageal reflux disease between 2006 and 2011 in Japan: a retrospective cohort study

      BMC Health Serv Res 2015 Feb:15:76

    • Kazuhisa Yamaguchi, Hiroya Taniguchi, Azusa Komori, Yukiya Narita, Sohei Nitta, Motoo Nomura, Shigenori Kadowaki, Daisuke Takahari, Takashi Ura, Masashi Andoh, Kei Muro, Keita Mori and Yoshinori Igarashi

      A single -arm phase-II trial of combined chemotherapy with S-1, oral leucovorin, and bevacizumab in heavily pre-treated patients with metastatic colorectal cancer

      BMC Cancer 15:601, 2015

    • Manabu Muto.

      Endoscopic disgnosis for superficial neoplasia at the head and neck regions.

      Eur J Cancer Prev. (in press)

  • 2014年

    • Takeshi Setoyama,Shinichi Miyamoto, Takahiro Horimatsu, Taro Funakoshi, Mitsuhiro Nikaido, Yuzo Kodama, Sachiko Minamiguchi, Tomoko Yamabata, Manabu Muto, Tsutomu Chiba.

      Bioactive insulin-like growth factors as a possible molecular target for non-islet cell tumor hypoglycemia.

      Cancer Biol Ther. 2014 Dec 2;15(12):1588-92.

    • Nishikawa Y, Tsuji Y, Isoda H, Kodama Y, Chiba T.

      Perfusion in the tissue surrounding pancreatic cancer and the patient’s prognosis

      Biomed Res Int 2014:Article ID 648021:2014.

    • Yamada A, Cox MA, Gaffney KA, Moreland A, Boland CR, Goel A.

      Technical Factors Involved in the Measurement of Circulating MicroRNA Biomarkers for the Detection of Colorectal Neoplasia.

      PLoS One. 2014 Nov 18;9(11):e112481.

    • Chikatoshi Katada, Manabu Muto, Satoshi Tanabe, Katsuhiko Higuchi, Tohru Sasaki, Mizutomo Azuma, Kenji Ishido, Natsuya Katada, Shinichi Sakuramoto, Keishi Yamashita, Takashi Masaki, Meijin Nakayama, Makito Okamoto, Wasaburo Koizumi.

      Factors associated with the presence of multiple Lugol-voiding lesions in patients with esophageal squamous-cell carcinoma.

      Dis Esophagus. 27(5):457-62,2014.

    • Shinya Ohashi, Osamu Kikuchi, Mihoko Tsurumaki, Yukie Nakai, Daisuke Kuriyama, Hiroi Kasai, Takahiro Horimatsu, Shin’ichi Miyamoto, Akira Shimizu, Tsutomu Chiba, Manabu Muto.
      Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma.

      PLOS ONE 2014 Aug 4;9(8):e103126.

    • Yoshiyuki Yukawa, Shinya Ohashi, Yusuke Amanuma, Yukie Nakai, Mihoko Tsurumaki, Osamu Kikuchi, Shin’ichi Miyamoto, Tsunehiro Oyama, Toshihiro Kawamoto, Tsutomu Chiba, Tomonari Matsuda, Manabu Muto.

      Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion.

      Am J Cancer Res2014 May 26;4(3):279-84. eCollection 2014.

    • Kagawa S, Natsuizaka M, Whelan KA, Facompre N, Naganuma S, Ohashi S, Kinugasa H, Egloff AM, Basu D, Gimotty PA, Klein-Szanto AJ, Bass AJ, Wong KK, Diehl JA, Rustgi AK, Nakagawa H.

      Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities

      Oncogene 34:2347-2359:2014.

    • Kanai M

      Therapeutic application of curcumin for patients with pancreatic cancer

      World Journal of Gastroenterology 20(28):9384-9391:2014

    • Watanabe N, Narimatsu H, Noh JY, Kunii Y, Mukasa K, Matsumoto M, Suzuki M, Sekiya K, Ohye H, Yoshihara A, Iwaku K, Kobayashi S, Kameyama K, Kobayashi K, Nishikawa Y, Kami M, Sugino K, Ito K

      Rituximab-including combined modality treatment for primary thyroid lymphoma: an effective regimen for elderly patients

      Thyroid. 24(6):994-999:2014.

    • Yamada A, Minamiguchi S, Sakai Y, Horimatsu T, Muto M, Chiba T, Boland CR, Goel A

      Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps

      PLoS One 9(5):e98059:2014

    • Peng Xue, Masashi Kanai, Yukiko Mori, Takafumi Nishimura, Norimitsu Uza, Yuzo Kodama, Yoshiya Kawaguchi, Kyoichi Takaori, Shigemi Matsumoto, Shinji Uemoto, Tsutomu Chiba.

      Comparative outcomes between initially unresectable and recurrent cases of advanced pancreatic cancer following palliative chemotherapy

      Pancreas 2014; 43(3):411-6

    • Funakoshi T, Yasui H, Boku N, Fukutomi A, Yamazaki K, Machida N, Todaka A, Tsushima T, Hamauchi S, Yokota T, Onozawa Y, Komatsu H, Endo M

      Clinicopathological features and outcomes of gastric cancer patients with pulmonary lymphangitis carcinomatosa

      Jpn J Clin Oncol. 44(9):792-798:2014.

    • Ikezawa K, Kanai M, Ajiki T, Tsukamoto T, Toyokawa H, Terajima H, Furuyama H, Nagano H, Ikai I, Kuroda N, Awane M, Ochiai T, Takemura S, Miyamoto A, Kume M, Ogawa M, Takeda Y, Taira K, Ioka T.

      Patients with recurrent biliary tract cancer have a better prognosis than those with unresectable disease: retrospective analysis of a multi-institutional experience with patients of advanced biliary tract cancer who received palliative chemotherapy

      J Hepatobiliary Pancreat Sci 21(2):98-104:2014

       

       

    • Kou T, Kanai M, Ikezawa K, Ajiki T, Tsukamoto T, Toyokawa H, Yazumi S, Terajima H, Furuyama H, Nagano H, Ikai I, Kuroda N, Awane M, Ochiai T, Takemura S, Miyamoto A, Kume M, Ogawa M, Takeda Y, Taira T, Ioka T

      Comparative Outcomes of Elderly and Non-elderly Patients Receiving First-Line Palliative Chemotherapy for Advanced Biliary Tract Cancer

      J Gastroenterol Hepatol 29:403-408:2014

    • Yamanaka K, Hatano E, Kanai M, Tanaka S, Yamamoto K, Narita M, Nagata H, Ishii T, Machimoto T, Taura K, Uemoto S.

      A single-center analysis of the survival benefits of adjuvant gemcitabine chemotherapy for biliary tract cancer

      J Clin Oncol 19(3):185-9, 2014.

    • Ueda K, Hirahashi J, Seki G, Tanaka M, Kushida N, Takeshima Y, Nishikawa Y, Fujita T, Nangaku M

      Successful treatment of acute kidney injury in patients with idiopathic nephrotic syndrome using human atrial natriuretic peptide

      Intern Med 53(8):865-869:2014.

    • Ueda K, Hirahashi J, Seki G, Tanaka M, Kushida N, Takeshima Y, Nishikawa Y, Fujita T, Nangaku M

      Successful treatment of acute kidney injury in patients with idiopathic nephrotic syndrome using human atrial natriuretic peptide

      Intern Med 53(8):865-869:2014.

    • Shimizu T, Marusawa H, Matsumoto Y, Inuzuka T, Ikeda A, Fujii Y, Minamiguchi S, Miyamoto S, Kou T, Sakai Y, Crabtree JE, Chiba T.

      Accumulation of somatic mutations in TP53 in gastric epithelium with Helicobacter pylori infection

      Gastroenterology. 2014;147(2):407-17.

    • Nikaido M, Miyamoto S, Iinuma S

      Systemic ulcerative lesions in a patient with ischemic heart disease

      Gastroenterology. 147: e7-8. 2014

    • Nishikawa Y, Tsubokura M, Kato S, Saito Y

      Possible Anisakiasis Associated with Fishery Resumption

      Disaster Med Public Health Prep 8(2):117-118:2014

       

    • Matsumoto T, Hasegawa S, Matsumoto S, Horimatsu T, Okoshi K, Yamada M, Kawada K, Sakai Y

      Overcoming the challenges of primary tumor management in patients with metastatic colorectal cancer unresectable for cure and an asymptomatic primary tumor

      Dis Colon Rectum 57(6):679-86:2014

    • Xue P, Kanai M, Mori Y, Nishimura T, Uza N, Kodama Y, Kawaguchi Y, Takaori K, Matsumoto S, Uemoto S

      Neutrophil-to-lymphocyte ratio for predicting palliative chemotherapy outcomes in advanced pancreatic cancer patients

      Cancer Med 3(2):406-415:2014

    • Toyoda M, Ajiki T, Fujiwara Y, Nagano H, Kobayashi S, Sakai D, Hatano E, Kanai M, Nakamori S, Miyamoto A, Tsuji A, Kaihara S, Ikoma H, Takemura S, Toyokawa H, Terajima H, Morita S, Ioka T.

      Phase I study of adjuvant chemotherapy with gemcitabine plus cisplatin in patients with biliary tract cancer undergoing curative resection without major hepatectomy (KHBO10004)

      Cancer Chemother Pharmacol. 2014 Jun;73(6):1295-1301.

    • Narita Y, Taniguchi H, Komori A, Nitta S, Yamaguchi K, Kondo C, Nomura M, Kadowaki S, Takahari D, Ura T, Andoh M, Muro K.

      CA19-9 level as a prognostic and predictive factor of bevacizumab efficacy in metastatic colorectal cancer patients undergoing oxaliplatin-based chemotherapy.

      Cancer Chemother Pharmacol.  2014 Feb;73(2):409-16.

    • Kobayashi S, Nagano H, Sakai D, Eguchi H, Hatano E, Kanai M, Seo S, Taura K, Fujiwara Y, Ajiki T, Takemurra S, Kubo S, Yanagimoto H, Toyokawa H, Tsuji A, Terajima H, Morita S, Ioka T.

      Phase I study of adjuvant gemcitabine or S-1 in patients with biliary tract cancers undergoing major hepatectomy

      Cancer Chemother Pharmacol 74:(4):669-709:2014.

    • Yoko Mashimo, Yasumasa Ezoe, Kosuke Ueda, Yoshinao Ozaki, Yusuke Amanuma, Ikuo Aoyama, Takahiro Horimatsu, Shuko Morita, Shinichi Miyamoto, Tomonori Yano, Koji Higashino, Tsutomu Chiba, Manabu Muto.

      Salvage photodynamic therapy is an effective and safe treatment for patients with local failure after definitive chemoradiotherapy for esophageal squamous cell carcinoma.

      Journal of Cancer Therapy (JCT) 5(7):647-656.2014.

    • Takeshi Setoyama, Shinichi Miyamoto, Takahiro Horimatsu, Shuko Morita, Yasumasa Ezoe, Manabu Muto, Go Watanabe, Eiji Tanaka, Tsutomu Chiba.

      Multimodal endoscopic treatment for delayed severe esophageal stricturecaused by incomplete stent removal.

      Dis Esophagus. 27(2):112-115.2014.

    • Shinya Yamada, Hisashi Doyama, Kenshi Yao, Noriya Uedo, Yasumasa Ezoe, Ichiro Oda, Kazuhiro Kaneko,Yoshiro Kawahara, Cshizu Yokoi, Yasushi Sugiura, Hideki Ishikawa, Yoji Takeuchi, Yutaka Saito, Manabu Muto.

      An efficient diagnostic strategy for small, depressed early gastric cancer with magnifying narrow-band imaging: a post-hoc analysis of a prospective randomized controlled trial.

      Gastrointest Endosc2014 Jan;79(1):55-63. 

  • 2013年

    • Nagai H, Kitano T, Nishimura T, Yasuda H, Nakata K, Takashima S, Kanai M, Matsumoto S, Mori Y, Kakudo Y, Sato H, Yamaguchi T, Kameno K, Kim YH, Mishima M, Yanagihara K.

      Use of glucose solution for the alleviation of gemcitabine-induced vascular pain: a double-blind randomized crossover study

      Support Care Cancer 21(12):3271-3278:2013.

    • Watanabe T, Tsuji Y, Takahashi N, Yoshida T, Tamaoki M, Kikuchi O, Watanabe Y, Kodama Y, Isoda H, Yamamoto H, Chiba T

      Relationship Between Pancreatic Perfusion Parameters and Clinical Complications of Severe Acute Pancreatitis

      Pancreas. 42(1):180-182, 2013

    • Takahashi Y, Nishikawa Y, Mori J, Hamaki T, Tanimoto T.

      Therapeutic platelet transfusion for hypoproliferative thrombocytopenia

      Lancet. 381(9868):724. 2013

    • Nishikawa Y, Tanimoto T, Tsubokura M, Kami M, Saito Y

      Treatment for patients with indolent and mantle cell lymphoma

      Lancet 382(9896):1093-4, 2013

    • Goto Y, Kodaira T, Fuwa N, Mizoguchi N, Nakahara R, Nomura M, Tomita N, Tachibana H.

      Alternating chemoradiotherapy in patients with nasopharyngeal cancer: prognostic factors and proposal for individualization of therapy.

      J Radiat Res 2013 Jan;54(1):98-107.

    • Nomura M, Inoue K, Matsushita S, Takahari D, Kondoh C, Shitara K, Ura T, Hayashi K, Kojima H, Kamata M, Tatematsu M, Hosoda R, Sawada S, Oka H, Muro K.

      Serum Concentration of Fentanyl During Conversion from Intravenous to Transdermal Administration to Patients with Chronic Cancer Pain

      Clin J Pain 2013 Jun;29(6):487-91.

    • Kanai M, Otsuka Y, Otsuka K, Sato M, Nishimura T, Mori Y, Kawaguchi M, Hatano E, Kodama Y, Matsumoto S, Murakami Y, Imaizumi A, Chiba T, Nishihira J, Shibata H.

      A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients.

      Cancer Chemother Pharmacol. 71(6):1521-30,2013.

    • Nomura M, Kamata M, Kojima H, Hayashi K, Sawada S.

      Irsogladine maleate reduces the incidence of fluorouracil-based chemotherapy-induced oral mucositis.

      Ann Oncol. 2013 Apr;24(4):1062-6.

    • Nishikawa Y, Okuda S, Takebayashi C, Tanimoto T, Kami M, Kobayashi K.

      A case of late onset erythropoietic protoporphyria associated with myelodysplastic syndrome treated by the combination of beta carotene and azacitidine

      Ann Hematol. 92(10):1415-6, 2013

    • Tatematsu N, Ezoe Y, Tanaka E, Muto M, Sakai Y, Tsuboyama T.

      Impact of neoadjuvant chemotherapy on physical fitness, physical activity, and health-related quality of life of patients with resectable esophageal cancer

      Am J Clin Oncol. 36(1):53-6, 2013.

       

    • Osamu Kikuchi, Yasumasa Ezoe, Shuko Morita, Takahiro Horimatsu, Manabu Muto.

      Narrow-band Imaging for the Head and Neck Region and the Upper Gastrointestinal Tract.

      Jpn J Clin Oncol  2013 May;43(5):458-65. 

    • Manabu Muto.

      Endoscopic diagnositic strategy of superficial esophageal squamous cell carcinoma.

      Dig Endosc.  2013 Mar;25 Suppl 1:1-6. 

    • Kohei Takizawa, Atsuo Takashima, Aya Kimura, Junki Mizusawa, Noriaki Hasuike, Hiroyuki Ono, Masanori Terashima, Manabu Muto, Narikazu Boku, Mitsuru Sasako and Haruhiko Fukuda for the Gastrointestinal Endoscopy Study Group (GIESG) and Stomach Cancer Study Group (SCSG) of the Japan Clinical Oncology Group (JCOG) .

      A Phase II Clinical Trial of Endoscopic Submucosal Dissection for Early Gastric Cancer of Undifferentiated Type: Japan Clinical Oncology Group Study JCOG1009/1010.

      Jpn J Clin Oncol2013 Jan;43(1):87-91. 

    • Chikatoshi Katada, Manabu Muto, Satoshi Tanabe, Katsuhiko Higuchi, Tohru Sasaki, Mizutomo Azuma, Kenji Ishido, Takashi Masaki, Meijin Nakayama, Makito Okamoto, Wasaburo Koizumi.

      Surveillance after endoscopic mucosal resection or endoscopic submucosal dissection for esophageal squamous cell carcinoma.

      Digestive Endosc2013 Mar;25 Suppl 1:39-43. 

  • 2012年

    • Ishii N, Setoyama T, Deshpande GA, Omata F, Matsuda M, Suzuki S, Uemura M, Iizuka Y, Fukuda K, Suzuki K, Fujita Y.

      Endoscopic band ligation for colonic diverticular hemorrhage.

      Gastrointest Endosc 2012; 75: 382-7.

    • Masayuki Watanabe, Hideo Baba, Chikashi Ishioka, Yasumasa Nishimura, Manabu Muto.

      Recent advances in diagnosis and treatment for malignancies of the gastrointestinal tract.

      Digestion. 85(2):95-98,2012

    • Masaki T, Katada C, Nakayama M, Takeda M, Miyamoto S, Seino Y, Matsuba H, Okamoto T, Koizumi W, Tanabe S, Horiguchi S, Okamoto M, Muto M.

      Usefulness and pitfall of Narrow band imaging combined with magnifying endoscopy for detecting an unknown head and neck primary site with cervical lymph node metastasis.

      Auris Nasus Larynx. 2012 Oct;39(5):502-6.

    • Saraya T, Ikematsu H, Fu KI, Tsunoda C, Yoda Y, Oono Y, Kojima T, Yano T, Horimatsu T, Sano Y, Kaneko K.

      Evaluation of complications related to therapeutic colonoscopy using the bipolar snare

      Surg Endosc. 26(2):533-40, 2012.

    • Kanai M, Guha S, Aggarwal BB.

      The potential role og curcumin for treatment of pancreatic cancer

      Pancreatic Cancer molecular mechanism and target. In Tech Books 2012 Chapter 12:213-224, 2012.

    • Ikematsu H1, Saito Y, Tanaka S, Uraoka T, Sano Y, Horimatsu T, Matsuda T, Oka S, Higashi R, Ishikawa H, Kaneko K.

      The impact of narrow band imaging for colon polyp detection: a multicenter randomized controlled trial by tandem colonoscopy.

      J Gastroenterol 47(10):1099-1107, 2012.

    • Kikuchi O , Mouri H , Matsueda K and Yamamoto H.

      Endoscopic submucosal dissection for treatment of patients gged 75 years and over with esophageal cancer.

      ISRN Gastroenterol 2012:671324, 2012.

    • Ohara Y, Kikuchi O, Goto T, Yoshida T, Mori H, Matsueda K, Yamamoto H.

      Successful treatment of a patient with sepsis and liver abscess caused by Edwardsiella tarda.

      Intern Med. 51:2813-2817, 2012.

    • Nomura M, Shitara K, Kodaira T, Hatooka S, Mizota A, Kondoh C, Yokota T, Takahari D, Ura T, Muro K.

      Prognostic Impact of the 6th and 7th American Joint Committee on Cancer TNM Staging Systems on Esophageal Cancer Patients Treated with Chemoradiotherapy.

      Int J Radiat Oncol Biol Phys. 2012;82:946-952.

    • Nomura M, Shitara K, Kodaira T, Kondoh C, Takahari D, Ura T, Kojima H, Kamata M, Muro K, Sawada S.

      Recursive Partitioning Analysis for New Classification of Patients with Esophageal Cancer Treated by Chemoradiotherapy.

      Int J Radiat Oncol Biol Phys.  2012 Nov 1;84(3):786-92.

    • Nagai H, Yasuda H, Hatachi Y, Xue D, Sasaki T, Yamaya M, Sakamori Y, Togashi Y, Masago K, Ito I, Kim YH, Mio T, Mishima M

      Nitric oxide (NO) enhances pemetrexed cytotoxicity via NO-cGMP signaling in lung adenocarcinoma cells in vitro and in vivo

      Int J Oncol  41(1):24-30, 2012.

    • Nomura M, Kamata M, Kojima H, Sawada S

      Renal salt-wasting syndrome associated with docetaxel in an esophageal cancer patient

      Int Canc Conf J  2012 1:67–69

    • Tsuji Y, Watanabe T, Kudo M, Arai H, Strober W, Chiba T.

      Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis

      Immunity.37(2):326-38, 2012.

    • Kondoh C, Takahari D, Shitara K, Mizota A, Nomura M, Yokota T, Ura T, Ito S, Kawai H, Sawaki A, Muro K.

      Efficacy of docetaxel in patients with paclitaxel-resistant advanced gastric cancer.

      Gan To Kagaku Ryoho 2012 Oct;39(10):1511-5.

    • Natsuizaka M, Naganuma S, Kagawa S, Ohashi S, Ahmadi A, Subramanian H, Chang S, Nakagawa KJ, Ji X, Liebhaber SA, Klein-Szanto AJ, Nakagawa H

      Hypoxia induces IGFBP3 in esophageal squamous cancer cells through HIF-1α-mediated mRNA transcription and continuous protein synthesis

      FASEB J 26(6):2620-30:2012.

    • Koyasu S, Isoda H, Tsuji Y, Yamamoto H, Matsueda K, Watanabe Y, Chiba T, Togashi K.

      Hepatic arterial perfusion increases in the early stage of severe acute pancreatitis patients: Evaluation by perfusion computed tomography

      Eur J Radiol. 81(1):43-6, 2012.

    • Yokoyama A, Ichimasa K, Ishiguro T, Mori Y, Ikeda H, Hayashi T, Minami H, Hyashi S, Watanabe G, Inoue H, Kudo SE

      Is it proper to use non-magnified narrow-band imaging for esophageal neoplasia screening? Japanese single-center, prospective study.

      Dig Endosc 24:412-8, 2012

    • Goto O, Fujishiro M, Oda I, Kakushima N, Yamamoto Y, Tsuji Y, Ohata K, Fujiwara T, Fujiwara J, Ishii N, Yokoi C, Miyamoto S, Itoh T, Morishita S, Gotoda T, Koike K.

      A multicenter survey of the management after gastric endoscopic submucosal dissection related to postoperative bleeding.

      Dig Dis Sci. 57(2):435-9, 2012.

    • Setoyama T, Miyamoto S, Fukuda K.

      Hemosuccus pancreaticus diagnosed with concurrent endoscopic retrograde pancreatography and selective angiography

      Clin Gastroenterol Hepatol. 10(4): A28, 2012.

    • Kanai M, Hatano E, Kobayashi S, Fujiwara Y, Sakai D, Kodama Y, Ajiki T, Nagano H, Ioka T

      Phase I trial of oral S-1 combined with gemcitabine and cisplatin for advanced biliary tract cancer

      Chemother Pharmacol.  69(5):1181-8, 2012.

    • Kanai M, Imaizumi A, Otsuka Y, Sasaki H, Hashiguchi M, Tsujiko K, Matsumoto S, Ishiguro H, Chiba T.

      Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers.

      Cancer Chemother Pharmacol. 69(1):65-70:2012.

    • Nomura M, Kodaira T, Furutani K, Tachibana H, Tomita N, Goto Y.

      Predictive factors for radiation pneumonitis in oesophageal cancer patients treated with chemoradiotherapy without prophylactic nodal irradiation.

      Br J Radiol.  2012 Jun;85(1014):813-8.

    • Shimatsu A, Kakeya H, Imaizumi A, Morimoto T, Kanai M, Maeda S

      Clinical application of “Curcumin”, a multi-functional substance

      Anti-Aging Medicine. 9(1):43-51, 2012.

    • Nishikawa Y, Hoshina K, Sasaki H, Hosaka A, Yamamoto K, Okamoto H, Shigematsu K, Miyata T.

      Acute remodeling of an adjoining aneurysm after endovascular treatment of a ruptured splanchnic arterial aneurysm: a case of clinically diagnosed segmental arterial mediolysis.

      Ann Vasc Dis. 5(4):449-53, 2012.

    • Naganuma S, Whelan KA, Natsuizaka M, Kagawa S, Kinugasa H, Chang S, Subramanian H, Rhoades B, Ohashi S, Itoh H, Herlyn M, Diehl JA, Gimotty PA, Klein-Szanto AJ, Nakagawa H.

      Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma.

      Am J Cancer Res 2(4):459-75, 2012.

    • Yoshiyuki Yukawa, Manabu Muto, Yusuke Amanuma, Yasumasa Ezoe,Yoko Mashimo, Kimiko Hori, Takahiro Horimatsu, Shuko Morita, Shinichi Miyamoto,Sashiko Minamiguchi, Tsutomu Chiba.

      Elimination of esophageal multiple precancerous lesions by chemotherapy: potential chemoprevention of metachronous multiple cancer development after curative treatment.

      Esophagus. 9(4):203-209.2012

    • Chikatoshi Katada, Manabu Muto, Meijin Nakayama, Satoshi Tanabe, Katsuhiko Higuchi, Tohru Sasaki, Mizutomo Azuma, Kenji Ishido,Natsuya Katada, Keishi Yamashita, Masayuki Nemoto, Tomotaka Shibata, Takashi Masaki, Makito Okamoto, Wasaburo Koizumi.

      Risk of superficial squamous cell carcinoma developing in the head and neck region in patients with esophageal squamous cell carcinoma.

      Laryngoscope. 2012 Jun;122(6):1291-6. 

    • Shinichi Miyamoto, Yoko Mashimo, Takahiro Horimatsu, Yasumasa Ezoe, Shuko Morita, Manabu Muto, Tsutomu Chiba.

      Cerebral air embolism caused by chemoradiotherapy for esophageal cancer.

      J Clin Oncol. 2012 Sep 1;30(25):e237-8. 

    • Yoshiyuki Yukawa, Manabu Muto, Kimiko Hori, Haruna Nagayoshi, Akira Yokoyama, Tsutomu Chiba, Tomonari Matsuda.

      Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde-derived DNA damage in the blood of Japanese alcoholics.

      Cancer Sci. 2012 Sep;103(9):1651-5. 

    • Takahiro Horimatsu, Shinichi Miyamoto, Yasumasa Ezoe, Manabu Muto, Akihiko Yoshizawa, Yoshiharu Sakai.

      Gastrointestinal: Case of early-stage squamous cell carcinoma of the anal canal diagnosed using narrow-band imaging system with magnification.

      J Gastroenterol Hepatol. 27(8):1406. 2012

    • Takahiro Horimatsu, Manabu Muto, Yusuke Yoda, Tomonori Yano, Yasumasa Ezoe, Shinichi Miyamoto, Tsutomu Chiba.

      Tissue damage in the canine normal esophagus by photoactivation with taraporfin sodium (Laserphyrin): A preclinical study.

      PLOS ONE. 2012;7(6):e38308. 

    • Tomonori Yano, Manabu Muto, Kenichi Yoshimura, Miyuki Niimi, Yasumasa Ezoe, Yusuke Yoda, Yoshinobu Yamamoto, Hogara Nishisaki, Koji HIgashino and Hiroyasu Iishi.

      Phase I study of photodynamic therapy using talaporfin sodium and diode laser for local failure after chemoradiotherapy for esophageal cancer.

      Radiat Oncol. 2012 Jul 23;7:113. 

    • Kimiko Hori, Shin’ichi Miyamoto, Yoshiyuki Yukawa, Manabu Muto, Tsutomu Chiba, Tomonari Matsuda.

      Stability of acetaldehyde-derived DNA adduct in vitro.

      Biochem a Biophys Res Commun. 423(4):642-646. 2012

    • Miyamoto S, Morita S, Muto M.

      Multiple early-stage malignant melanoma of the esophagus with a long follow-up period after endoscopic treatment: report of a case and a literature review

      Esophageal Cancer -Cell and Molecular Biology, Biomarkers, Nutrition and Treatment Croatia:

      INTECH 2012;227-238

    • Tsubasa Watanabe, Shinichi Miyamoto, Koji Kitagori, Takahiro Horimatsu, Shuko Morita, Yoko Mashimo, Yasumasa Ezoe, Manabu Muto, Tsutomu Chiba.

      A case of long-term survival of metastatic small round cell tumor treated with multimodal therapy.

      Oncol Let. 3(1):30-34.2012

    • Tsunehiro Oyama, Hidetaka Uramoto, Norio Kagawa, Takashi Yoshimatsu, Toshihiro Osaki, Ryoichi Nakanishi, Hisao Nagaya, Kazuhiro Kaneko, Manabu Muto, Toshihiro Kawamoto, Fumihiro Tanaka, Akinobu Gotoh.

      Cytochrome P450 in non-small cell lung cancer related to exogenous chemical metabolism.

      Front Biosci S4,1539-1546.2012

    • Tomonori Yano, Manabu Muto, Keiko Minashi, Junko Iwasaki, Takashi Kojima, Nozomu Fuse, Toshihiko Doi, Kazuhiro Kaneko, Atsushi Ohtsu.

      Photodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: a phase II study.

      Int J Cancer. 131(5):1228-1234. 2012

    • Manabu Muto, Yasumasa Ezoe, Tomonori Yano, Ikuo Aoyama, Yusuke Yoda, Keiko Minashi, Shuko Morita, Takahiro Horimatsu, Shin-ichi Miyamoto, Atsushi Ohtsu, Tsutomu Chiba.

      Usefulness of endoscopic radial incision and cutting method for refractory esophagogastric anastomotic stricture

      Gastrointest Endosc 75:965-72, 2012

  • 2011年

    • Ohashi S, Natsuizaka M, Naganuma S, Kagawa S, Kimura S, Itoh H, Kalman RA, Nakagawa M, DarlingDS, Basu D, Gimotty PA, Klein-Szanto AJ,Diehl AJ,  Herlyn M, and Nakagawa H:

      A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT competent cells that express the ZEB transcription factors.

      Cancer Res 2011 Sep ;71(21):6836-47.

    • Ohashi S, Natsuizaka M, Nakagawa H:

      MMP7 and activation of IGF-1R: A new insight into anti-EGFR therapeutic resistance in metastatic colorectal cancer.

      Cancer Biology & Therapy. 2011 Jan 15; 11(2), 184-187

    • Akitake R, Miyamoto S, Nakamura F, Horimatsu T, Ezoe Y, Muto M, Chiba T.

      Early Detection of 5-FU-Induced Acute Leukoencephalopathy on Diffusion-Weighted MRI.

      Jpn J Clin Oncol.2011 Jan;41(1):121-4

    • Tu CH, Muto M, Horimatsu T,Taku K, Yano T, Minashi K, Onozawa M, Nihei K, Ishikura S, Ohtsu A, Yoshida S.

      Submucosal tumor appearance is a useful endoscopic predictor of early primary-site recurrence after definitive chemoradiotherapy for esophageal squamous cell carcinoma.

      Dis Esophagus.2011 May;24(4):274-8

    • Mashimo Y, Horimatsu T, Miyamoto S.

      Umbilical Metastasis (Sister Mary Joseph’s Nodule) From Esophageal Squamous Cell Carcinoma.

      Clin Gastroenterol Hepatol. 2011 Aug;9(8):A20

    • Yuki Asada, Manabu Muto, Tomonori Yano, Keiko Minashi, Satoshi Fujii,Atsushi Ochiai, Atsushi Ohtsu, Shigeaki Yoshida.

      Successful Endosocpic Submucosal Dissection for Esophageal Squamous Cell Carcinoma together with a Lipoma.

      Hepato-Gastroenterology. 58(110-111):1595-1597.2011

    • Nomura M, Kamata M, Kojima H, Hayashi K, Kozai M, Sawada S.

      Six- versus 12-h conversion method from intravenous to transdermal fentanyl in chronic cancer pain: a randomized study.

      Support Care Cancer. 2011 May;19(5):691-5. Epub 2010 Jun 13.

    • Kobayashi N, Ueki K, Okazaki Y, Iwane A, Kubota N, Ohsugi M, Awazawa M, Kobayashi M, Sasako T, Kaneko K, Suzuki M, Nishikawa Y, Hara K, Yoshimura K, Koshima I, Goyama S, Murakami K, Sasaki J, Nagai R, Kurokawa M, Sasaki T, Kadowaki T.

      Blockade of class IB phosphoinositide-3 kinase ameliorates obesity-induced inflammation and insulin resistance

      Proc Natl Acad Sci USA. 2011:108(14):5753-8.

    • Hirota M, Tsuda M, Tsuji Y, Kanno A, Kikuta K, Kume K, Hamada S, Unno J, Ito H, Ariga H, Chiba T, Masamune A, Satoh K, Shimosegawa T

      Perfusion Computed Tomography Findings of Autoimmune Pancreatitis.

      Pancreas. 40(8):1295-301, 2011.

       

       

    • Mizota A, Shitara K, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Muro K.

      A Retrospective Comparison of Docetaxel and Paclitaxel for Patients with Advanced or Recurrent Esophageal Cancer Who Previously Received Platinum-Based Chemotherapy.

      Oncology 2011 Nov 17;81(3-4):237-242.

       

       

    • Inoue K, Matsushita S, Nomura M, et al.

      Determination of fentanyl drug in cancer patient serum by liquid chromatography with mass spectrometry.

      Jpn J Pharm Palliat Care Sci  2011;4:111-116.

       

       

    • Shitara K, Mizota A, Yatabe Y, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Muro K.

      Lapatinib Plus Trastuzumab for a Patient with Heavily Pre-treated Gastric Cancer that Progressed after Trastuzumab.

      Jpn J Clin Oncol. 2011 May;41(5):663-5.

       

    • Zaima C, Kanai M, Ishikawa S, Kawaguchi Y, Masui T, Mori Y, Nishimura T, Matsumoto S, Yanagihara K, Chiba T, Mimori T

      A case of progressive digital ischemia after early withdrawal of gemcitabine and S-1 in a patient with systemic sclerosis

      Jpn J Clin Oncol. 2011 Jun;41(6):803-6.

    • Shitara K, Oze I, Mizota A, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Yuki S, Komatsu Y, Matsuo K, Muro K.

      Randomized Phase II Study Comparing Dose Escalated Weekly Paclitaxel vs. Standard Dose Weekly Paclitaxel for Patients with Previously Treated Advanced Gastric Cancer.

      Jpn J Clin Oncol 2011 Feb;41(2):287-90.

       

       

    • Ueda K, Muto M, Chiba T.

      Unusual esophageal ulcer caused by Alendronate Sodium

      Gastrointest Endosc. 73(5):1037-8:2011

    • Nakanishi Y, Miyamoto S, Ishizu S, Seno H, Muto M, Chiba T,

      An unusual cause of dysphagia after endoscopic resection of an early esophageal cancer.

      Endoscopy .43 Suppl 2 UCTN:E156-7. 2011

    • Yano T, Muto M, Minashi K, Kaneko K, Onozawa M, Nihei K, S Ishikura, A Ohtsu.

      Long-term results of salvage photodynamic therapy for patients with local failure after chemoradiotherapy for esophageal squamous cell carcinoma.

      Endoscopy. 43(8):657-63:2011

    • Mizota A, Shitara K, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Muro K.

      A case of heavily pretreated rectal cancer with disseminated intravascular coagulation that improved following reintroduction of FOLFOX plus bevacizumab.

      Int J Clin Oncol 2011;16:766-769.

    • Nagai H, Tanaka S, Niimi M, Seo N, Sasaki T, Date H, Mishima M, Yasuda H, Yanagihara K.

      Safety of erlotinib treatment in outpatients with previously treated non-small-cell lung cancer in Japan

      Int J Clin Oncol 2011:16(5):560-567.

    • Mizota A, Shitara K, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Inaba Y, Yamaura H, Sato Y, Kato M, Muro K.

      Retrospective analysis of cetuximab monotherapy for patients with irinotecan-intolerant metastatic colorectal cancer.

      Int J Clin Oncol 2011 Aug;16(4):416-20.

    • Shitara K, Matsuo K, Mizota A, Kondo C, Nomura M, Takahari D, Yokota T, Ura T, Ito S, Sawaki A, Tajika M, Kawai H, Muro K.

      Association of fluoropyrimidines, platinum agents, taxanes, and irinotecan in any line of chemotherapy with survival in patients with advanced gastric cancer.

      Gastric Cancer. 2011 Jun;14(2):155-60. Epub 2011 Feb 23.

    • Mizota A, Shitara K, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Muro K.

      FOLFOX plus cetuximab for a patient with metastatic colorectal cancer with icterus due to multiple liver metastases.

      Gan To Kagaku Ryoho.  2011 Jul;38(7):1205-8.

    • Kishimoto M, Tsuji Y, Katabami N, Shimizu J, Lee KJ, Iwasaki T, Miyake YI, Yazumi S, Chiba T, Yamada K.

      Measurement of canine pancreatic perfusion using dynamic computed tomography: influence of input-output vessels on deconvolution and maximum slope methods

      Eur J Radiol 77(1):175-81, 2011.

    • Alaboudy AA, Elbahrawy A, Matsumoto S, Yoshizawa A.

      Conventional narrow-band imaging has good correlation with histopathological severity of Helicobacter pylori gastritis

      Dig Dis Sci 54(4):1127-1130, 2011.

    • Kanai M, Yoshimura K, Tsumura T, Asada M, Suzuki C, Niimi M, Matsumoto S, Nishimura T, Nitta T, Yasuchika K, Taura K, Mori Y, Hamada A, Inoue N, Tada S, Yanagihara K, Yazumi S, Osaki Y, Chiba T, Ikai I, Fukushima M, Uemoto S, Hatano E.

      A multi-institution phase II study of gemcitabine/S-1 combination chemotherapy for patients with advanced biliary tract cancer

      Cancer Chemother Pharmacol. 67(6):1429-34, 2011.

    • Shitara K, Matsuo K, Oze I, Mizota A, Kondo C, Nomura M, Yokota T, Takahari D, Ura T, Muro K.

      Meta-analysis of neutropenia or leukopenia as a prognostic factor in patients with malignant disease undergoing chemotherapy.

      Cancer Chemother Pharmacol. 2011 Aug;68(2):301-7. Epub 2010 Oct 20. Review.

    • Kanai M, Ishiguro H, Mori Y, Kitano T, Nishimura T, Matsumoto S, Yanagihara K, Chiba T, Toi M.

      Temporary blood pressure drop after bevacizumab administration is associated with clinical course of advanced colorectal cancer

      Br J Cancer. 105(11):1693-6, 2011.

       

    • Yokota T, Hatooka S, Ura T, Abe T, Takahari D, Shitara K, Nomura M, Kondo C, Mizota A, Yatabe Y, Shinoda M, Muro K.

      Docetaxel plus 5-Fluorouracil and Cisplatin (DCF) Induction Chemotherapy for Locally Advanced Borderline-resectable T4 Esophageal Cancer.

      Anticancer Res. 2011 Oct;31(10):3535-41.

    • Watanabe T, Tsuji Y, Kodama Y, Isoda H, Yamamoto H, Chiba T.

      Relationship between serum angiopoietin-2 level and perfusion CT parameters in severe acute pancreatitis

      Am J Gastroenterol. 106(10):1859-61.

    • Aoyagi K, Minashi K, H Igaki, Tachimori Y, Nisimura T, Hokamura N, Ashida A, Daiko H, Ochiai A, Muto M, Ohtsu A, Yoshida T, H Sasaki.

      Artificially induced epithelail mesenchymal transition in surgical subjects: its implications in clinical and basic cancer research.

      PLOS ONE. 21;6(4):2011

    • Matsuba H, Katada C, Masaki T, Nakayama M, Okamoto T, Hanaoka N, Tanabe S, Koizumi Wasaburo, Okamoto M, Muto M.

      Diagnosis of the extent of advanced oropharyngeal and hypopharyngeal cancers by narrow band imaging with magnifying endoscopy.

      The Laryngoscope.121(4):753-9:2011

    • Muto M, Morita S, Ezoe Y, Horimatsu T, Miyamoto S, Yoshii T, Iizuka T, Chiba T.

      Macroscopic Estimation of Submucosal Invasion in the Esophagus.

      Tec Gastrointest Endosc. 13(1);8-13: 2011

    • Matsubara J, Honda K, Ono M, Tanaka Y, Kobayashi M, Jung G, Yanagisawa K, Sakuma T, Nakamori S, Sata N, Nagai H, Ioka T, Okusaka T, Kosuge T, Tsuchida A, Shimahara M, Yasunami Y, Chiba T, Hirohashi S, Yamada T.

      Reduced plasma level of CXC chemokine ligand 7 in patients with pancreatic cancer.

      Cancer Epidemiol Biomarkers Prev. 2011; 20: 160-71.

    • Matsubara J, Shimada Y, Kato K, Nagai Y, Iwasa S, Nakajima TE, Hamaguchi T, Yamada Y, Takagi S, Kobayashi K, Yoshioka A, Nakayama N,Tsuji A:

      Phase II study of bolus 5-fluorouracil and leucovorin combined with weekly paclitaxel (FLTAX) as first-line therapy for advanced gastric cancer.

      Oncology 2011; 81: 291-297

    • Matsubara J, Honda K, Ono M, Sekine S, Tanaka Y, Kobayashi M, Jung G, Sakuma T, Nakamori S, Sata N, Nagai H, Ioka T, Okusaka T, Kosuge T,Tsuchida A, Shimahara M, Yasunami Y, Chiba T, Yamada T:

      Identification of adipophilin as a potential plasma biomarker for colorectal cancer using label-free quantitative mass spectrometry and protein microarray.

      Cancer Epidemiol Biomarkers Prev 2011; 20: 2195-2203.

    • Ezoe Y, Muto M, Uedo N, Doyama H, Yao K, Oda I, Kaneko K, Kawahara Y, Yokoi C, Sugiura Y, Ishikawa H, Takeuchi Y, Kaneko Y, Saito Y

      Magnifying Narrowband Imaging Is More Accurate than Conventional White-Light Imaging in Diagnosis of Gastric Mucosal Cancer

      Gastroenterology 141(6);2017-2025:2011

    • Muto M, Satake H, Yano T, Minashi K, Hayashi R, Fujii S, Ochiai A, Ohtsu A, Morita S, Horimatsu T, Ezoe Y, Miyamoto S, Asato R, Tateya I, Yoshizawa A, Chiba T

      Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer

      Gastrointest Endosc 74(3);477-484:2011

    • Muto M, Higuchi H, Ezoe Y, Horimatsu T, Morita S, Miyamoto S, Chiba T

      Differences of image enhancement in image-enhanced endoscopy: narrow band imaging versus flexible spectral imaging color enhancement

      J Gastroenterol 46(8);998-1002:2011

    • Horimatsu T, Miyamoto S, Morita S, Mashimo Y, Ezoe Y, Muto M, Chiba T

      Pharmacokinetics of oxaliplatin in a hemodialytic patient treated with modified FOLFOX-6 plus bevacizumab therapy

      Cancer Chemother Pharmacol 68(1);263-266:2011

    • Ezoe Y, Fujii S, Muto M, Ochiai A, Ohtsu A

      Epidermoid metaplasia of the esophagus: endoscopic features and differential diagnosis

      Hepatogastroenterol 58(107-108);809-813:2011

    • Miyamoto S, Konda Y, Matsui M, Sawada K, Ikeda K, Watanabe N, Kawanami C, Chiba T.

      Acute airway obstruction in a patient with achalasia.

      Intern Med. 2011;50(20):2333-6.

    • Ezoe Y, Muto M, Horimatsu T, Morita S, Miyamoto S, Mochizuki S, Minashi K, Yano T, Ohtsu A, Chiba T.

      Efficacy of preventive endoscopic balloon dilation for esophageal stricture after endoscopic resection.

      J Clin Gastroenterol. 45;222-227:2011.

    • Yamada A, Notohara K, Aoyama I, Miyoshi M, Miyamoto S, Fujii S, Yamamoto H.

      Endoscopic features of sessile serrated adenoma and other serrated colorectal polyps.

      Hepato-Gastroenterol. 2011; 58: 45-51.

    • Yamada A, Fujii S, Daiko H, Nishimura M, Chiba T, Ochiai A.

      Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.

      Int J Oncol. 2011; 38(2): 345-353.

    • Matsubara J:

      [review article] Biomarkers in molecularly targeted therapy for cancer.

      Recent Pat Biomarkers 2011; 1: 110-118.

    • Saraya T, Ikematsu H, Fu KI, Tsunoda C, Yoda Y, Oono Y, Kojima T, Yano T, Horimatsu T,et al.
      Evaluation of complications related to therapeutic colonoscopy using the bipolar snare.

      Surg Endosc. 2011 Sep 23.

  • 2010年

    • Ohashi S, Natsuizaka M, Yashiro-Ohtani Y, Kalman RA, Nakagawa M, Wu L, Klein-Szanto AJ, Herlyn M, Diehl AJ, Katz JP, Pear WS, Seykora JT, and Nakagawa H:

      NOTCH1 and NOTCH3 cordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.

      Gastroenterology 2010 Dec; 139 (6): 2113-23.

    • Ohashi S, Natsuizaka M, Wong GS, Michaylira CZ, Grugan KD, Stairs DB, Kalabis J, Vega ME, Kalman RA,

      Nakagawa M, Klein-Szanto AJ, Herlyn M, Diehl JA, Rustgi AK, Nakagawa H.

      Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcriptional factors.

      Cancer Res, 2010 May 15; 70(10): 4174-84.

    • Muto M, Minashi K, Yano T, Saito Y, Oda I, Nonaka S, Omori T, Sugiura H, Goda K, Kaise M, Inoue H, Ishikawa H, Ochiai A, Shimoda T, Watanabe H, Tajiri H, Saito D.

      Early detection of superficial squamous cell carcinoma in the head and nec region and esophagus by narrow band imaging: a multicenter randomized controlled trial.

      J Clin Oncol, 28(9):1566-1572 2010

    • Katada C, tanabe S, Koizumi W, Higuchi K, Sasaki T, Azuma M, Katada N, Masaki T, Nakayama M, Okamoto M, Muto M,

      Narrow band imaging for detecting superficial squamous cell carcinoma of the head neck in patients with esophageal squmaous cell carcinoma.

      Endoscopy, 42(3):185-90 2010

    • Hayashi T, Muto M, Hayashi R, Ugumori T, Kishimoto S, Ebihara S.

      Usefulness of Narrow Band Imaging for detecting the primary tumor site in patients with primary unknown cervical lymph node metastasis.

      Jpn J Clin Oncol, 40 (6):537-541 2010

    • Fujii S, Yamazaki M, Muto M, Ochiai A.

      Microvascular irregularities are associated with composition of squamous epithelial lesion and correlate with subepithelial invasion of superficial type pharyngeal squamous cell carcinoma.

      Histopathology, 56(4):510-522 2010

    • Ezoe Y, Muto M, Horimatsu T, Minashi K, Yano T, Chiba T, Ohtsu A.

      Magnifying narrow-band imaging versus magnifying white-light imaging for the differential diagnosis of gastric small depressive lesions: a prospective study.

      Gastrointest Endosc.2010 Mar;71(3) :477-84.

    • Matsunaka T, Miyamoto S, Shitara K, Ochiai A, Chiba T.

      Ligand-specific antibodies to insulin-like growth factors suppress intestinal polyp formation in apc+/- mice.

      Mol Cancer Ther. 2010;9(2):419-28.

    • Kitagori K, Miyamoto S, Sakurai T.

      Adenocarcinoma derived from Brunner’s gland.

      Clin Gastroenterol Hepatol 2010;8(4):A26

    • Matsubara J, Ono M, Honda K, Negishi A, Ueno H, Okusaka T, Furuse J, Furuta K, Sugiyama E, Saito Y, Kaniwa N, Sawada J, Shoji A, Sakuma T, Chiba T, Saijo N, Hirohashi S, Yamada T:

      Survival prediction for pancreatic cancer patients receiving gemcitabine treatment.

      Mol Cell Proteomics 2010; 9: 695-704.

    • Matsubara J, Hirashima Y and Yamada Y:

      Impact of HER2, EGFR, IGF-1R, and VEGFR expressions on the outcome of chemotherapy for advanced gastric cancer.

      Gan To Kagaku Ryoho 2010; 37: 1489-1496.

  • 2009年

    • Harima Y, Ikeda K, Utsunomiya K, Shiga T, Komemushi A, Kojima H, Nomura M, Kamata M, Sawada S.

      Identification of genes associated with progression and metastasis of advanced cervical cancers after radiotherapy by cDNA microarray analysis.

      Int J Radiat Oncol Biol Phys. 2009;75(4):1232-9.

    • Muto M, Horimatsu T, Ezoe Y, Morita S, Miyamoto S.

      Improving visualization techniques by narrow band imaging and magnification endoscopy.

      J Gastroenterol Hepatol.2009 Aug;24(8):1333-46.

    • Morita S, Miyamoto S, Matsumoto S, Muto M, Chiba T.

      Multiple early-stage malignant melanoma of the esophagus with long follow-up period after endoscopic treatment: report of a case.

      Esophagus 2009;6(4):249-252.

    • Kurokawa Y, Muto M, Minashi K, Boku N, and Fukuda H, for the Gastrointestinal Oncology Study Group of Japan Clinical Oncology Group (JCOG).

      A phase II trial of combined treatment of endoscopic mucosal resection and chemoradiotherapy for clinical stage I esophageal carcinoma: Japan Clinical Oncology Group Study JCOG0508.

      Jpn J Clin Oncol. 39(10):686-9, 2009

    • Onozawa M, Nihei K, Oshikura S, Minashi K, Yano T, Muto M, Ohtsu A, Ogino T.

      Elective nodal irradiation (ENI) in definitive chemoradiotherapy (CRT) for squamous cell carcinoma of the thoracic esophagus.

      Radiotherapy and Oncol.92(2):266-9, 2009

    • Kaltenbach T, Muto M, Soetikno R, Dev P, Okamura K, Hahm J, Shimizu S.

      Teleteaching endoscopy: the feasibility of real-time, uncompressed video transmission by using advanced-network technologies.

      Gastrointest Endosco.70(5):1013-7, 2009

    • Yokoyama A, Kumagai Y, Yokoyama T, Omori T, Kato H, Igaki H, Tsujinaka T, Muto M, Yokoyama M, Watanabe H.

      Health risk appraisal models for mass screening for esophageal and pharyngeal cancer: an endoscopic follow-up study of cancer-free Japanese men.

      Cancer Epidemiol Biomarkers Prev. 18(2):651-5, 2009

    • Ugumori T, Muto M, Hayashi R, Hayashi T, Kishimoto S.

      Prospective study of early detection of pharyngeal superficial carcinoma with the narrowband imaging laryngoscope.

      Head Neck. 31(2):189-94, 2009

    • Muto M, Horimatsu T, Ezoe Y, Hori K, Yukawa Y, Morita S, Miyamoto S, Chiba T.

      Narrow-band imaging of the gastrointestinal tract.

      J Gastroenterol. 2009;44(1):13-25.

    • Fujiwara M, Miyamoto S, Iguchi K, Matsunaka T, Sakashita H, Tsuruyama T, Kanegane H, Marusawa H, Nakase H, Chiba1 T.

      Acute Epstein-Barr Virus infection presenting as severe gastroenteritis without infectious mononucleosis-like manifestations.

      Clin J Gastroenterol 2009;2:398-403.

    • Akitake R, Nakase H, Ueno S, Miyamoto S, Iehara N, Chiba T.

      Involvement of Lupus Enteritis in a Patient with Lupus Cystitis and Nephritis.

      Digestion 2009;80:160-164.

    • Horimatsu T, Sano Y, Kaneko K, Ikematsu H, Katagiri A, Yano T, Fu K, Muto M, Fujii S, Ochiai A, Yoshida S.

      Relationship between MVD and meshed-capillaries using magnifying NBI colonoscopy in colorectal precursor lesions.

      Hepatogastroenterology. 2009;56(90) :372-7.

    • Horimatsu T, Yano T, Doi T, Fujii S, Kaneko K.

      Complete resection of alpha-fetoprotein-producing early gastric cancer by using endoscopic submucosal dissection.

      Gastrointest Endosc.2009 Mar;69(3) :565-6.

    • Sano Y, Ikematsu H, Fu KI, Emura F, Katagiri A, Horimatsu T, Kaneko K, Soetikno R, Yoshida S.

      Meshed capillary vessels by use of narrow-band imaging for differential diagnosis of small colorectal polyps.

      Gastrointest Endosc. 2009;69(2):278-83.

    • Matsubara J, Ono M, Negishi A, Ueno H, Okusaka T, Furuse J, Furuta K, Sugiyama E, Saito Y, Kaniwa N, Sawada J, Honda K, Sakuma T, Chiba T, Saijo N, Hirohashi S, Yamada T:

      Identification of a predictive biomarker for hematologic toxicities of gemcitabine.

      J Clin Oncol 2009; 27: 2261-2268.

    • Matsubara J, Ono M and Yamada T:

      [review article] Predictive markers for chemotherapy toxicity: an important factor in personalized therapy.

      Eur J Clin Med Oncol 2009; 1: 1-6.

    • Takai A, Setoyama T, Miyamoto S.

      Pancreatic Somatostatinoma With vonRecklinghausen’s Disease.

      Clin Gastroenterol Hepatol 2009;7(5):A28.

  • 2008年

    • Muto M.

      Endoscopic diagnosis and treatment of superficial cancer in the oropharynx and hypopharynx.

      In “New challenges in gastrointestinal endoscopy”, P67-76, ed. H. Tajiri and K Yasuda, Springer (Tokyo), 2008

    • Yokoyama T, Yokoyama A, Kumagai Y, Omori T, Kato H, Igaki H, Tsujinaka T, Muto M, Yokoyama M, and Watanabe H.

      Health risk appraisal models for mass screening of esophageal cancer in japanese men.

      Cancer Epidem Biomark & Prev 17(10):2846-2854, 2008

    • Komemushi A, Tanigawa N, Kariya S, Kojima H, Shomura Y, Tokuda T, Nomura M, Terada J, Kamata M, Sawada S

      Intraosseous Venography with Carbon Dioxide in Percutaneous Vertebroplasty: Carbon Dioxide Retention in Renal Veins.

      Cardiovasc Intervent Radiol 2008;31(6):1174-1177

    • Yano T, Muto M, Hattori S, Minashi K, Onozawa M, Nihei K, Ishikura S, Ohtsu A, Yoshida S.

      Long-term results of salvage endoscopic mucosal resection in patients with local failure after definitive chemoradiotherapy for esophageal squamous cell carcinoma.

      Endoscopy 40(9):717-721, 2008

    • Oyama T, Sugio K, Isse T, Matsumoto A, Nose N, Urammoto H, Nozoe T, Morita M, Kagawa N, Osaki T, Muto M, Yasumoto K, Kawamoto T.

      Expression of cytochrome P450 in non-small cell lung cancer.

      Frontiers in Bioscience 13,5787-5793, 2008

    • Fuse N, Doi T, Ohtsu A, Yano T, Hamamoto Y, Minashi K, Tahara M, Muto M, Asaka M, Yoshida S.

      Safety of irinotecan and infusional fluorouracil/leucovorin (FOLFIRI) in Japan: a retrospective review of 48 patients with metastatic colorectal cancer.

      Int J of Clin Oncol,13:144-149,2008

    • Katagiri A, Fu KI, Sano Y, Ikematsu H, Horimatsu T, Kaneko K, Muto M, Yoshida S.

      Narrow band imaging with magnifying colonoscopy as a diagnostic tool for predicting the histology of early colorectal neoplasia.

      Alim Pharm & Therap 27(12):1269-74,2008

    • Sangai T, Fujimoto H, Miyamoto S, Maeda H, Nakamura M, Ishii G, Nagai K, Nagashima T, Miyazaki M, Ochiai A.

      Roles of osteoclasts and bone-derived IGFs in the survival and growth of human breast cancer cells in human adult bone implanted into nonobese diabetic/severe combined immunodeficient mice.

      Clin Exp Metastasis. 2008;25(4):401-10.

    • Yamada A, Sasaki H, Aoyagi K, Sano M, Fujii S, Daiko H, Nishimura M, Yoshida T, Chiba T, Ochiai A.

      Expression of cytokeratin 7 predicts survival in stage I/IIA/IIB squamous cell carcinoma of the esophagus.

      Oncol Rep. 2008;20(5):1021-7.

    • Matsubara J, Nishina T, Yamada Y, Moriwaki T, Shimoda T, Kajiwara T, Nakajima TE, Kato K, Hamaguchi T, Shimada Y, Okayama Y, Oka T, Shirao K:

      Impacts of excision repair cross-complementing gene 1 (ERCC1), dihydropyrimidine dehydrogenase, and epidermal growth factor receptor on the outcomes of patients with advanced gastric cancer.

      Br J Cancer 2008; 98: 832-839.

    • Matsubara J, Okusaka T, Morizane C, Ikeda M, Ueno H:

      Ultrasound-guided percutaneous pancreatic tumor biopsy in pancreatic cancer: a comparison with metastatic liver tumor biopsy, including sensitivity, specificity, and complications.

      J Gastroenterol 2008; 43: 225-232.

    • Matsubara J, Yamada Y, Hirashima Y, Takahari D, Okita NT, Kato K, Hamaguchi T, Shirao K, Shimada Y, Shimoda T:

      Impact of insulin-like growth factor type 1 receptor (IGF-1R), epidermal growth factor receptor (EGFR), and HER2 expressions on outcomes of patients with gastric cancer.

      Clin Cancer Res 2008; 14: 3022-3029.

    • Matsubara J, Yamada Y, Nakajima TE, Kato K, Hamaguchi T, Shirao K, Shimada Y, Shimoda T:

      Clinical significance of insulin-like growth factor type 1 receptor and epidermal growth factor receptor in patients with advanced gastric cancer.

      Oncology 2008; 74: 76-83.

    • Matsubara J, Shimada Y, Takashima A, Takahari D, Hirashima Y, Okita NT, Nakajima TE, Kato K, Hamaguchi T, Yamada Y, Shirao K:

      A phase I study of bolus 5-fluorouracil and leucovorin combined with weekly paclitaxel (FLTAX) as first-line therapy for advanced gastric cancer.

      Jpn J Clin Oncol 2008; 38: 540-546.

    • Matsumoto S, Nishimura T, Kanai M, Mori Y, Nagayama S, Kawamura J, Nomura A, Miyamoto S, Kitano T, Ishiguro H, Yanagihara K, Teramukai S, Sakai Y, Chiba T, Fukushima M.

      Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study.

      Chemotherapy 2008;54:395-403.

    • Yamada A, Sasaki H, Aoyagi K, Sano M, Fujii S, Daiko H, Nishimura M, Yoshida T, Chiba T, Ochiai A.

      Expression of cytokeratin 7 predicts survival in stage I/IIA/IIB squamous cell carcinoma of the esophagus.

      Oncol Rep. 2008;20(5):1021-7.

  • 2007年

    • Muto M, Ochiai A, Yoshida S.

      Detection of superficial cancer in the oropharyngeal and hypopharyngeal mucosal sites and the value of NBI at qualitative diagnosis. In “Advanced Digestive Endoscopy: comprehensive Atlas of High Resolution Endoscopy and Narrowband lmaging”,P35-48, Edited by Jonathan cohen.

      Blackwell publishing 2007

    • Minashi K. Muto M. Ohtsu A.

      Non-surgical treatment of superficial esophageal squamous cell carcinoma.

      Esophagus. 4,159-164, 2007

    • Takeuchi S, Ohtsu A, Doi T, Kojima T, Minashi K, Mera K, Yano T, Tahara M, Muto M, Nihei K.

      A retrospective study of definitive chemoradiotherapy for elderly patients with esophageal cancer.

      Am J Clin Oncol. ;30(6):607-11, 2007

    • Minegishi Y, Tsukino H, Muto M, Goto K, Gemma A, Tsugane S, Kudoh S, Nishiwaki Y, Esumi H.

      Susceptibility to lung cancer and genetic polymorphisms in the alcohol metabolite-related enzymes alcohol dehydrogenase 3, aldehyde dehydrogenase 2, and cytochrome p450 2E1 in the Japanese population.

      Cancer 110:353-362, 2007

    • Fuse N, Doi T, Ohtsu A, Takeuchi S, Kojima T, Taku K, Tahara M, Muto M, Asaka M, Yoshida S.

      Feasibility of oxaliplatin and infusional fluorouracil/leucovorin (FOLFOX4) for Japanese patients with unresectable metastatic colorectal cancer.

      Jpn J Clin Oncol.;37(6):434-9, 2007

    • Muto M, Fujishiro M, Sato Y, Niwa Y, Kaise M, Kato M, Takubo K.

      Multicenter study design of the ex vivo evaluation of endocytoscopy in esophageal squamous cell carcinoma.

      Dig Endosc 19:S153-5, 2007

    • Maekawa K, Saeki M, Saito Y, Ozawa S, Kurose K, Kawamoto M, Kamatani N, Kato K, Hamaguchi T, Yamada Y, Shirao K, Shimada Y, Muto M, Doi T, Ohtsu A, Yoshida T, Matsumura Y, Saijo N, Sawada J.

      Genetic variation and haplotype structures of the DVS gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences.

      J Hum Genetics 52(10):804-819, 2007

    • Katada C, Muto M, Momma K, Arima M, Tajiri H, Kanamaru C, Ooyanagi H, Endo H, Michida T, Hasuike N, Oda I, Fujii T, Saito D.

      Clinical outcome after endoscopic mucosal resection for esophageal squamous cell carcinoma invading the muscularis mucosae-a multicenter retrospective cohort study.

      Endoscopy 39:779-783, 2007

    • Fujishiro M, Takubo K, Sato Y, Kaise M, Niwa Y, Kato M, Muto M.

      Potential and present limitation of endocytoscopy in the diagnosis of esophageal squamous-cell carcinoma: A multicenter ex vivo pilot study.

      Gastrointest Endosc 66:551-555,2007

    • Asakage T, Yokoyama A, Haneda T, Yamazaki M, Manabu Muto, Yokoyama T, Kato H, Igaki H, Tsujinaka T, Kumagai Y, Yokoyama M, Omori T, and Watanabe H.

      Genetic polymorphisms of alcohol and aldehyde dehydrogenases, and drinking, smoking and diet in Japanese men with oral and pharyngeal squamous cell carcinoma.

      Carcinogenesis. 28: 865 – 874.2007

    • Oyama T, Isse T, Ogawa M, Muto M, Uchiyama I, Kawamoto T.

      Susceptibility to inhalation toxicity of acetaldehyde in Aldh2 knockout mice.

      Frontiers in Bioscience 12:1927-1934, January 1, 2007

    • Miyamoto S, Nakamura M, Yano K, Ishii G, Hasebe T, Endoh Y, Sangai T, Maeda H, Shi-Chuang Z, Chiba T, Ochiai A.

      Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.

      Cancer Sci. 2007;98(5):685-91

    • Horimatsu T, Fu KI, Sano Y , Matsuda T, Fujimori T, Yoshida S.

      Acute appendicitis as a rare complication after endoscopic mucosal resection.

      Dig Dis Sci. 2007 Jul;52(7):1741-4.

    • Fu KI, Horimatsu T, Sano Y, Katagiri A, Fujimori T.

      Metastasis to the appendix from gastric cancer detected incidentally on colonoscopy.

      Endoscopy. 2007.

    • Ito T, Tanaka E, Kadowaki T, Kan T, Higashiyama M, Shiojima S, Tomoda S, Myoumoto A, Akiyama H, Nobumasa H, Matsumoto S, Miyamoto S, Mitsumori M, Sato F, Watanabe G, Itami A, Meltzer SJ, Tsujimoto G, Shimada Y.

      An ultrasensitive new DNA microarray chip provides gene expression profiles for preoperative esophageal cancer biopsies without RNA amplification.

      Oncology 2007;73:366-75.

  • 2006年

    • Ohashi S, Yazumi S, Nishio A, Fukui T, Asada M, Chiba T.

      Acute cerebral infarction during combination chemotherapy with s-1 and cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach.

      Internal Medicine. 2006;45(18):1049-53.

    • Ohashi S, Yazumi S, Watanabe N, Matsumoto S, Fukui T, Nishio A, Chiba T.Education and imaging.

      MALT lymphoma of the terminal ileum.

      Journal of Gastroenterology and Hepatology, 2006 Sep;21(9):1495.

    • Ohashi S, Nishio A, Nakamura H, Asada M, Tamaki H, Kawasaki K, Fukui T, Yodoi J, Chiba T.

      Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice.

      Antioxidants & Redox Signaling. 2006 Sep-Oct;8(9-10):1835-45.

    • Ohashi S, Nishio A, Nakamura H, Kido M, Kiriya K, Asada M, Tamaki H, Fukui T, Kawasaki K, Watanabe N, Yodoi J, Okazaki K, Chiba T.

      Clinical Significance of Serum Thioredoxin-1 Levels in Patients with Acute Pancreatitis.

      Pancreas. 2006 Apr;32(3):264-70.

    • Ohashi S, Nishio A, Nakamura H, Kido M, Ueno S, Uza N, Inoue S, Kitamura H, Kiriya K, Asada M, Tamaki H, Matsuura M, Kawasaki K, Fukui T, Watanabe N, Nakase H, Yodoi J, Okazaki K, and Chiba T.

      Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis.  

      Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G772-81.

    • Sano Y, Horimatsu T, Fu K I, Katagiri A, Muto M, and Ishikawa H.

      Magnifying observation of microvascualr architecture of colorectal lesions using a Narrow-band-imaging system.

      Digestive Endoscopy, Volume 18, Issue s1, Page S44-S51Jul 2006.

    • Fujii M, Sakashita M, Wakamura K, Horimatsu T, Tanaka S, Obata D, Iwamoto K, Okabayashi Y.

      Multiple gastric ulcers caused by a rice cake as an intragastric foreign body.

      J Gastroenterol. 2006 Mar;41(3):282-3.

    • Fujisawa T, Horimatsu T, Sakaguchi K, Onishi Y, Takeda A, Kishi M, Maeda M,and Nishigami T.

      Duodenal adenoma of gastric foveolar phenotype in the second portion of the duodenum.

      Digestive Endoscopy, Volume 18, Issue 1, Page 62-66, Jan 2006.

    • Goya M, Ishii G, Miyamoto S, Hasebe T, Nagai K, Yonou H, Hatano T, Ogawa Y, Ochiai A.

      Prostate-specific antigen induces apoptosis of osteoclast precursors: potential role in osteoblastic bone metastases of prostate cancer.

      Prostate 2006;66:1573-84.

    • Fukui T, Sakurai T, Miyamoto S, Ueno S, Kido M, Kiriya K, Inoue S, Ohashi S, Nishio A, Chiba T.

      Gastrointestinal: Epidermal metaplasia of the esophagus.

      J Gastroenterol Hepatol 2006;21:1627.

  • 2005年

    • Araki K, Sangai T, Miyamoto S, Maeda H, Shi-Chuang Z, Nakamura M, Ishii G, Hasebe T, Kusaka H, Akiyama T, Tokuda Y, Nagai K, Minami H, Ochiai A.

      Inhibition of bone-derived insulin-like growth factor of human multiple myeloma in the human adult bone explanted in NOD/SCID mouse.

      Int J Cancer 2005;118:2602-8

    • Nakamura M, Miyamoto S, Maeda H, Ishii G, Hasebe T, Chiba T, Asaka M, Ochiai A.

      Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability.

      Biochem Biophys Res Commun 2005;333:1011-16

    • Muto M, Miyamoto S, Hosokawa A, Doi T, Ohtsu A, Yoshida S, Endo Y, Hosokawa K, Saito D, Shim CS, Gossner L.

      Endoscopic mucosal resection in the stomach using the insulated-tip needle-knife.

      Endoscopy 2005;37:178-82

    • Miyamoto S, Nakamura M, Shitara K, Nakamura K, Ohki Y, Ishii G, Goya M, Kodama K, Sangai T, Maeda H, Shi-Chuang Z, Chiba T, Ochiai A.

      Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers.

      Clin Cancer Res 2005;11:3494-502

    • Sangai T, Ishii G, Kodama K, Miyamoto S, Aoyagi Y, Ito T, Magae J, Sasaki H, Nagashima T, Miyazaki M, Ochiai A.

      Effect of differences in cancer cells and tumor growth sites on recruiting bone marrow-derived endothelial cells and myofibroblasts in cancer-induced stroma.

      Int J Cancer 2005;115:885-92.

    • Kodama K, Ishii G, Miyamoto S, Goya M, Zhang SC, Sangai T, Yoshikawa T, Hasebe T, Hitomi Y, Izumi K, Ochiai A.

      Laminin 5 expression protects against anoikis at aerogenous spread and lepidic growth of human lung adenocarcinoma.

      Int J Cancer 2005;116:876-84.

  • 2004年

    • Nakamura M, Miyamoto S, Maeda H, Zhang S, Sangai T, Ishii G, Hasebe T, Endoh Y, Saitoh N, Asaka M, Ochiai A.

      Low levels of insulin-like growth factor type 1 receptor expression can predict the hepatic metastasis in Dukes’ C human colorectal cancers.

      Clin Cancer Res 2004;10:8434-41

    • Goya M, Miyamoto S, Ohki Y, Nakamura K, Shitara K, Maeda H, Sangai T, Kodama K, Endoh Y, Ishii G, Hasebe T, Nagai K, Yonou H, Hatano T, Ogawa Y, Ochiai A.

      Growth inhibition of human prostate cancer cells in human adult bone implanted into non-obese diabetic/severe combined immunodeficient mice by a ligand-specific antibody to human insulin-like growth factors.

      Cancer Res 2004;64:6252-8

    • Miyamoto S, Endoh Y, Hasebe T, Ishii G, Kodama K, Goya M, Ono M, Saitoh N, Chiba T, Ochiai A.

      Nuclear ?-catenin accumulation as a prognostic factor in Dukes’ D human colorectal cancers.

      Oncol Rep 2004;12:245-51

    • Miyamoto S, Yano K, Sugimoto S, Ishii G, Hasebe T, Endoh Y, Kodama K, Goya M, Chiba T, Ochiai A.

      Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.

      Cancer Res 2004;64:665-71

    • Lim SC, Zhang S, Ishii G, Endoh Y, Kodama K, Miyamoto S, Hayashi R, Ebihara S, Cho JS, Ochiai A.

      Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue.

      Clin Cancer Res 2004;10:166-72.

    • Kusakai G, Suzuki A, Ogura T, Miyamoto S, Ochiai A, Kaminishi M, Esumi H.

      ARK5 expression in colorectal cancer and its implications for tumor progression.

      Am J Pathol 004;164:987-95.

    • Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Miyamoto S, Ogura T, Ochiai A, Esumi H.

      Regulation of caspase-6 and FLIP by the AMPK family member ARK5.

      Oncogene 2004;23:7067-75.